Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 5/20 | 0.62 |
| ▸ | RAB9A | P51151 | 6/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.59 |
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | USP2 | O75604 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | STAT3 | P40763 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8747808 | 1.00 | RARB (0.62) | RARBRAB9ASMN1; SMN2MAPTHSD17B10 | |
| SCHEMBL5888400 | 1.00 | RARB (0.62) | RARBRAB9ASMN1; SMN2MAPTHSD17B10 | |
| SCHEMBL8075234 | 1.00 | RARB (0.62) | RARBRAB9ASMN1; SMN2MAPTHSD17B10 | |
| SCHEMBL9272426 | 1.00 | RARB (0.62) | RARBRAB9ASMN1; SMN2MAPTHSD17B10 | |
| SCHEMBL8631186 | 1.00 | RARB (0.62) | RARBRAB9ASMN1; SMN2MAPTHSD17B10 | |
| SCHEMBL8918716 | 1.00 | RARB (0.62) | RARBRAB9ASMN1; SMN2MAPTHSD17B10 | |
| SCHEMBL7723530 | 0.98 | RARB (0.60) | RARBRAB9ASMN1; SMN2MAPTHSD17B10 | |
| SCHEMBL10793104 | 0.93 | RARB (0.54) | RARBRAB9ASMN1; SMN2MAPTHSD17B10 | |
| SCHEMBL8917053 | 0.88 | MAPT (0.65) | RARBRAB9ASMN1; SMN2MAPTHSD17B10 | |
| SCHEMBL7677484 | 0.88 | MAPT (0.65) | RARBRAB9ASMN1; SMN2MAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5849216-A | Compounds for use in liquid-crystal mixtures | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-12-15 | — | — | US | disclosed |
| US-5707545-A | OPTICAL APPARATUS FOR ELCTRONICS | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-01-13 | — | — | US | disclosed |
| US-5366657-A | Esters or ethers for electrooptical apparatus | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-11-22 | — | — | US | disclosed |
| US-5344585-A | Switching; electrooptic display devices; high speed response | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-09-06 | — | — | US | disclosed |
| US-5250218-A | Liquid crystal composition, liquid crystal device, display apparatus and display method | CANON KABUSHIKI KAISHA (JP) | 1993-10-05 | — | — | US | disclosed |
| US-5071589-A | Additionally contain dope | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-12-10 | — | — | US | disclosed |