Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.65 |
| ▸ | RAB9A | P51151 | 4/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.65 |
| ▸ | MEN1 | O00255 | 2/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.65 |
| ▸ | USP2 | O75604 | 1/20 | 0.65 |
| ▸ | GAA | P10253 | 1/20 | 0.65 |
| ▸ | HPGD | P15428 | 1/20 | 0.65 |
| ▸ | RARB | P10826 | 7/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | RARA | P10276 | 1/20 | 0.49 |
| ▸ | MTOR | P42345 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | STAT3 | P40763 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 2/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7677484 | 1.00 | MAPT (0.65) | MAPTRAB9AHSD17B10ALDH1A1SMN1; SMN2 | |
| SCHEMBL9331469 | 0.91 | MAPT (0.77) | MAPTRAB9AHSD17B10ALDH1A1SMN1; SMN2 | |
| SCHEMBL8631186 | 0.88 | RARB (0.62) | MAPTRAB9AHSD17B10ALDH1A1SMN1; SMN2 | |
| SCHEMBL5888400 | 0.88 | RARB (0.62) | MAPTRAB9AHSD17B10ALDH1A1SMN1; SMN2 | |
| SCHEMBL8075234 | 0.88 | RARB (0.62) | MAPTRAB9AHSD17B10ALDH1A1SMN1; SMN2 | |
| SCHEMBL8918716 | 0.88 | RARB (0.62) | MAPTRAB9AHSD17B10ALDH1A1SMN1; SMN2 | |
| SCHEMBL8747808 | 0.88 | RARB (0.62) | MAPTRAB9AHSD17B10ALDH1A1SMN1; SMN2 | |
| SCHEMBL8713869 | 0.88 | RARB (0.62) | MAPTRAB9AHSD17B10ALDH1A1SMN1; SMN2 | |
| SCHEMBL9272426 | 0.88 | RARB (0.62) | MAPTRAB9AHSD17B10ALDH1A1SMN1; SMN2 | |
| SCHEMBL7517234 | 0.88 | RAB9A (0.71) | MAPTRAB9AHSD17B10ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5651918-A | Optically active 1,3-dioxolane derivatives carrying a mesogenic radical in the 4-position, a process for their preparation and their use as doping agents in liquid-crystal mixtures | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-07-29 | — | — | US | disclosed |