Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8716244 | 0.80 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2LMNAHTTCYP1A2 | |
| SCHEMBL29455782 | 0.78 | ALDH1A1 (0.32) | ALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL8713217 | 0.77 | ALDH1A1 (0.31) | ALDH1A1SMN1; SMN2HSP90AA1HSP90AB1 | |
| SCHEMBL8714063 | 0.76 | ALDH1A1 (0.32) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL12811732 | 0.76 | HSP90AA1 (0.38) | ALDH1A1SMN1; SMN2LMNAHTTCYP1A2 | |
| SCHEMBL8716967 | 0.75 | MEN1 (0.36) | ALDH1A1SMN1; SMN2LMNACYP1A2CYP3A4 | |
| SCHEMBL4047614 | 0.74 | HSP90AA1 (0.37) | ALDH1A1SMN1; SMN2LMNAHTTCYP1A2 | |
| SCHEMBL29561615 | 0.74 | HSP90AA1 (0.37) | ALDH1A1SMN1; SMN2LMNAHTTCYP1A2 | |
| SCHEMBL8747110 | 0.73 | ALDH1A1 (0.33) | ALDH1A1SMN1; SMN2LMNAHTTCYP1A2 | |
| Hydrochloric Acid SCHEMBL8717770 | 0.73 | EZH2 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5770772-A | 4-FORMYLAMINO-2,3,5-TRIMETHYL-1-(2-METHYL-2-PROPENYLOXY) -BENZENE; ARTERIOSCLEROSIS, BRAIN AND CARDIOVASCULAR DISORDERS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-06-23 | — | — | US | disclosed |
| US-5594154-A | 5-AMINO-2-BROMOMETHYL-2,4,6,7-TETRAMETHYL-2,3-DIHYDROBENZO(B) FURANS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-01-14 | — | — | US | disclosed |
| US-5478844-A | Method of using aminocoumaran derivatives for treating cerebrovascular diseases | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-12-26 | — | — | US | disclosed |
| EP-0483772-B1 | Aminocoumaran derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1995-09-13 | — | — | EP | disclosed |
| US-5376681-A | Aminocoumaran derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-12-27 | — | — | US | disclosed |
| CN-1071165-A | Aminocoumaran derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1993-04-21 | — | — | CN | disclosed |
| EP-0483772-A1 | Aminocoumaran derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-05-06 | — | — | EP | disclosed |