Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC2A1 | P11166 | 3/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | PNMT | P11086 | 1/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 5/20 | 0.38 |
| ▸ | MIF | P14174 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 4/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8714163 | 1.00 | TAAR1 (0.42) | TAAR1SLC6A2SLC2A1ESR1ESR2 | |
| SCHEMBL8713870 | 0.85 | TAAR1 (0.47) | TAAR1SLC6A2SLC2A1ESR1ESR2 | |
| SCHEMBL8713871 | 0.85 | TAAR1 (0.47) | TAAR1SLC6A2SLC2A1ESR1ESR2 | |
| SCHEMBL8713237 | 0.82 | PPARG (0.43) | PNMTADRB1HTR2AHTR2BADRB3 | |
| SCHEMBL8713241 | 0.82 | PPARG (0.43) | PNMTADRB1HTR2AHTR2BADRB3 | |
| SCHEMBL8716169 | 0.77 | SLC2A1 (0.45) | SLC6A2SLC2A1PNMTADRB1ADRA1A | |
| SCHEMBL8716164 | 0.77 | SLC2A1 (0.45) | SLC6A2SLC2A1PNMTADRB1ADRA1A | |
| SCHEMBL8717068 | 0.74 | SLC2A1 (0.45) | SLC6A2SLC2A1PNMTADRB1ADRA1A | |
| SCHEMBL8717066 | 0.74 | SLC2A1 (0.45) | SLC6A2SLC2A1PNMTADRB1ADRA1A | |
| SCHEMBL8718900 | 0.74 | SLC6A4 (0.49) | SLC6A2SLC2A1PNMTADRB1ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811293-A | CULTURE PRODUCT AS CHEMICAL INTERMEDIATE FOR ANTI-OBESITY AGENT | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1998-09-22 | — | — | US | disclosed |