Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | REN | P00797 | 3/20 | 0.41 |
| ▸ | LDHA | P00338 | 1/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CTSD | P07339 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | PNMT | P11086 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8713241 | 1.00 | PPARG (0.43) | PPARGPPARDPPARAACHEALOX15 | |
| SCHEMBL8714129 | 0.87 | LDHA (0.48) | PPARGPPARDPPARAACHEALOX15 | |
| SCHEMBL8714130 | 0.87 | LDHA (0.48) | PPARGPPARDPPARAACHEALOX15 | |
| SCHEMBL8433901 | 0.86 | ALOX15 (0.51) | PPARGPPARDPPARAACHEALOX15 | |
| SCHEMBL8433300 | 0.86 | ALOX15 (0.51) | PPARGPPARDPPARAACHEALOX15 | |
| SCHEMBL8714034 | 0.85 | ACHE (0.44) | PPARGPPARDPPARAACHEALOX15 | |
| SCHEMBL8714037 | 0.85 | ACHE (0.44) | PPARGPPARDPPARAACHEALOX15 | |
| SCHEMBL8713251 | 0.84 | SMN1; SMN2 (0.47) | PPARGPPARDPPARAACHEALOX15 | |
| SCHEMBL8713254 | 0.84 | SMN1; SMN2 (0.47) | PPARGPPARDPPARAACHEALOX15 | |
| SCHEMBL8714159 | 0.82 | TAAR1 (0.42) | ADRB3ADRB2HTR2AHTR2BPNMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811293-A | CULTURE PRODUCT AS CHEMICAL INTERMEDIATE FOR ANTI-OBESITY AGENT | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1998-09-22 | — | — | US | disclosed |