Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 2/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.38 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.37 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.37 |
| ▸ | XPO1 | O14980 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TACR1 | P25103 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4251643 | 0.78 | MAPT (0.44) | HDAC3HDAC6HDAC1HDAC2CES2 | |
| SCHEMBL440959 | 0.72 | CES2 (0.58) | CES2MAPTRAPGEF4XPO1ALDH1A1 | |
| SCHEMBL7216715 | 0.72 | CES2 (0.48) | CES2MAPTRAPGEF4XPO1AR | |
| SCHEMBL4564009 | 0.72 | CES2 (0.48) | CES2MAPTRAPGEF4XPO1AR | |
| SCHEMBL8712668 | 0.71 | TSHR (0.38) | LMNAGAA | |
| SCHEMBL13949254 | 0.71 | HDAC3 (0.40) | HDAC3HDAC6HDAC1HDAC2CES2 | |
| SCHEMBL16234266 | 0.71 | CES2 (0.46) | CES2MAPTRAPGEF4XPO1AR | |
| SCHEMBL22861023 | 0.71 | GABRB2 (0.52) | CES2MAPTRAPGEF4XPO1AR | |
| SCHEMBL1104677 | 0.71 | GABRB2 (0.52) | CES2MAPTRAPGEF4XPO1AR | |
| SCHEMBL16628066 | 0.70 | MAPT (0.50) | HDAC3HDAC6HDAC1HDAC2CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998006709-A1 | CYCLIC UREA COMPOUNDS, THEIR PRODUCTION AND USE AS HERBICIDES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-02-19 | — | — | WO | disclosed |