Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | MDH1 | P40925 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.46 |
| ▸ | SLC6A7 | Q99884 | 6/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | GPR6 | P46095 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 1/20 | 0.38 |
| ▸ | ACACA | Q13085 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8711563 | 0.94 | ADRA2A (0.45) | ADRA2AADORA3CHRM1MAOATBXA2R | |
| SCHEMBL8711077 | 0.93 | OPRM1 (0.51) | ADRA2AADORA3CHRM1MAOATBXA2R | |
| SCHEMBL8713901 | 0.93 | ADRA2A (0.46) | ADRA2AADORA3CHRM1MAOATBXA2R | |
| SCHEMBL8707737 | 0.92 | ADRA2A (0.44) | ADRA2AADORA3CHRM1MAOATBXA2R | |
| SCHEMBL8712141 | 0.92 | ADRA2A (0.45) | ADRA2AADORA3CHRM1MAOATBXA2R | |
| SCHEMBL7869792 | 0.91 | ADRA2A (0.43) | ADRA2AADORA3CHRM1MAOATBXA2R | |
| SCHEMBL8714433 | 0.90 | ADRA2A (0.44) | ADRA2AADORA3CHRM1MAOATBXA2R | |
| SCHEMBL8709684 | 0.89 | ADRA2A (0.47) | ADRA2AADORA3CHRM1MAOATBXA2R | |
| SCHEMBL8713892 | 0.89 | PARP1 (0.44) | SLC6A7HSD11B1MEN1KMT2AGPR6 | |
| SCHEMBL8713761 | 0.88 | ADRA2A (0.48) | ADRA2AADORA3CHRM1MAOATBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998054140-A1 | NOVEL TEREPHTHALAMIDE DERIVATIVES | DONGWHA PHARMACEUTICAL IND. CO., LTD. (KR) | 1998-12-03 | — | — | WO | disclosed |