Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 1/20 | 0.49 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.46 |
| ▸ | CFD | P00746 | 3/20 | 0.46 |
| ▸ | TPSB2 | P20231 | 3/20 | 0.46 |
| ▸ | F11 | P03951 | 2/20 | 0.46 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.43 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.43 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.43 |
| ▸ | PPIA | P62937 | 1/20 | 0.42 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.41 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.41 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.41 |
| ▸ | DHFR | P00374 | 1/20 | 0.41 |
| ▸ | MME | P08473 | 1/20 | 0.40 |
| ▸ | ACE | P12821 | 1/20 | 0.40 |
| ▸ | CPA1 | P15085 | 1/20 | 0.40 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8714445 | 1.00 | ADRB3 (0.49) | ADRB3SLC1A5CFDTPSB2F11 | |
| SCHEMBL8716922 | 0.89 | CFD (0.47) | CFDTPSB2F11PTGER1PTGER4 | |
| SCHEMBL8716924 | 0.89 | CFD (0.47) | CFDTPSB2F11PTGER1PTGER4 | |
| SCHEMBL8720148 | 0.85 | ADRB3 (0.44) | ADRB3 | |
| SCHEMBL8720151 | 0.85 | ADRB3 (0.44) | ADRB3 | |
| SCHEMBL8716324 | 0.84 | MAOB (0.49) | ADRB3 | |
| SCHEMBL8716321 | 0.84 | MAOB (0.49) | ADRB3 | |
| SCHEMBL8713862 | 0.83 | PNMT (0.50) | ADRB3 | |
| SCHEMBL8719065 | 0.81 | HDAC8 (0.43) | ADRB3 | |
| SCHEMBL8719067 | 0.81 | HDAC8 (0.43) | ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811293-A | CULTURE PRODUCT AS CHEMICAL INTERMEDIATE FOR ANTI-OBESITY AGENT | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1998-09-22 | — | — | US | disclosed |