Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.62 |
| ▸ | CA1 | P00915 | 2/20 | 0.62 |
| ▸ | CA2 | P00918 | 2/20 | 0.62 |
| ▸ | CA9 | Q16790 | 2/20 | 0.62 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.57 |
| ▸ | CA7 | P43166 | 1/20 | 0.57 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.57 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.53 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.53 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.52 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.48 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.47 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2636899 | 0.87 | CA12 (0.66) | CA12CA1CA2CA9OPRM1 | |
| SCHEMBL14031243 | 0.84 | CA12 (0.62) | CA12CA1CA2CA9OPRM1 | |
| SCHEMBL521915 | 0.81 | CA12 (0.58) | CA12CA1CA2CA9OPRM1 | |
| SCHEMBL18701791 | 0.81 | CA12 (0.58) | CA12CA1CA2CA9OPRM1 | |
| SCHEMBL14902437 | 0.80 | HRH3 (0.56) | CA12CA1CA2CA9OPRM1 | |
| SCHEMBL3455405 | 0.80 | OPRM1 (0.59) | CA12CA1CA2CA9OPRM1 | |
| SCHEMBL13756098 | 0.80 | OPRD1 (0.61) | CA12CA1CA2CA9OPRM1 | |
| SCHEMBL17799245 | 0.79 | CA12 (0.73) | CA12CA1CA2CA9OPRM1 | |
| SCHEMBL3278422 | 0.79 | CA12 (0.56) | CA12CA1CA2CA9OPRM1 | |
| SCHEMBL8161869 | 0.79 | CA12 (0.72) | CA12CA1CA2CA9CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998031669-A1 | NOVEL ARYLPIPERAZINE DERIVED FROM PIPERIDINE AS ANTIDEPRESSANT MEDICINES | PIERRE FABRE MEDICAMENT (FR) | 1998-07-23 | — | — | WO | disclosed |