Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 3/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8711875 | 0.83 | CHRNB2 (0.43) | CHRNB2CHRNA4THRBHTT | |
| SCHEMBL8711500 | 0.68 | CHRNB2 (0.47) | CHRNB2CHRNA4THRBHTT | |
| SCHEMBL8711504 | 0.68 | CHRNB2 (0.47) | CHRNB2CHRNA4THRBHTT | |
| SCHEMBL16684575 | 0.64 | CHRNB2 (0.47) | CHRNB2CHRNA4THRBHTT | |
| SCHEMBL8714147 | 0.64 | MAPT (0.38) | CHRNB2CHRNA4THRBHTT | |
| SCHEMBL8714145 | 0.64 | MAPT (0.38) | CHRNB2CHRNA4THRBHTT | |
| Hydrochloric Acid SCHEMBL5949846 | 0.59 | CHRNB2 (0.47) | CHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL2417312 | 0.59 | CHRNB2 (0.47) | CHRNB2CHRNA4 | |
| SCHEMBL9491863 | 0.59 | — | — | |
| SCHEMBL8711729 | 0.58 | CHRNB2 (0.50) | CHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5830902-A | SQUALENE SYNTHASE INHIBITOR | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1998-11-03 | — | — | US | disclosed |
| EP-0812840-A1 | NOVEL QUINUCLIDINE DERIVATIVES HAVING TRICYCLIC FUSED HETERO RING | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1997-12-17 | — | — | EP | disclosed |