Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 8/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | THPO | P40225 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ADAMTS4 | O75173 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | GMNN | O75496 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8716899 | 0.93 | HTT (0.49) | HSD11B1HTTTDP1LMNAKMT2A | |
| SCHEMBL8712536 | 0.91 | HTT (0.53) | HSD11B1HTTTDP1LMNAKMT2A | |
| SCHEMBL8717997 | 0.90 | HTT (0.47) | HSD11B1HTTTDP1LMNAKMT2A | |
| SCHEMBL8714689 | 0.90 | HSD11B1 (0.50) | HSD11B1HTTTDP1LMNAKMT2A | |
| SCHEMBL8714721 | 0.90 | HTT (0.53) | HSD11B1HTTTDP1LMNAKMT2A | |
| SCHEMBL8715137 | 0.89 | HSD11B1 (0.49) | HSD11B1HTTTDP1LMNAKMT2A | |
| SCHEMBL8712275 | 0.89 | HSD11B1 (0.54) | HSD11B1HTTTDP1LMNAKMT2A | |
| SCHEMBL8718638 | 0.89 | HTT (0.46) | HSD11B1HTTTDP1LMNAKMT2A | |
| SCHEMBL8712187 | 0.89 | HSD11B1 (0.52) | HSD11B1HTTTDP1LMNAKMT2A | |
| Hydrochloric Acid SCHEMBL8715324 | 0.88 | HSD11B1 (0.53) | HSD11B1HTTTDP1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5728835-A | HYPOTENSIVE AGENTS; ANTIISCHEMIC AGENTS | TOA EIYO, LTD. (JP) | 1998-03-17 | — | — | US | disclosed |