Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 2/20 | 0.67 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.61 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.61 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30363681 | 0.80 | PNMT (1.00) | PNMTSLC6A2SLC6A3TAAR1MAOA | |
| SCHEMBL14478283 | 0.80 | PNMT (1.00) | PNMTSLC6A2SLC6A3TAAR1MAOA | |
| SCHEMBL266685 | 0.80 | PNMT (1.00) | PNMTSLC6A2SLC6A3TAAR1MAOA | |
| SCHEMBL5018736 | 0.80 | PNMT (0.43) | PNMTSLC6A2SLC6A3MAOA | |
| Hydrochloric Acid SCHEMBL30559514 | 0.79 | PNMT (0.96) | PNMTSLC6A2SLC6A3TAAR1MAOA | |
| SCHEMBL6959170 | 0.78 | IDO1 (0.44) | PNMTSLC6A2SLC6A3SLC6A4 | |
| SCHEMBL586783 | 0.76 | SLC6A2 (1.00) | PNMTSLC6A2SLC6A3TAAR1MAOA | |
| SCHEMBL8440406 | 0.76 | PNMT (0.41) | PNMTSLC6A2SLC6A3 | |
| SCHEMBL22229845 | 0.76 | SLC6A2 (1.00) | PNMTSLC6A2SLC6A3TAAR1MAOA | |
| SCHEMBL267030 | 0.76 | SLC6A2 (1.00) | PNMTSLC6A2SLC6A3TAAR1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3083594-A1 | SUBSTITUTED BIPIPERIDINYL DERIVATIVES AS ADRENORECEPTOR ALPHA 2C ANTAGONISTS | Bayer Pharma Aktiengesellschaft (DE) | 2016-10-26 | — | — | EP | disclosed |
| WO-2015091415-A1 | SUBSTITUTED BIPIPERIDINYL DERIVATIVES AS ADRENORECEPTOR ALPHA 2C ANTAGONISTS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2015-06-25 | — | — | WO | disclosed |
| WO-1998006709-A1 | CYCLIC UREA COMPOUNDS, THEIR PRODUCTION AND USE AS HERBICIDES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-02-19 | — | — | WO | disclosed |