Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.41 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.41 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 3/20 | 0.38 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ANPEP | P15144 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8944351 | 0.76 | CYP2C19 (0.47) | KDM4ECYP1A2HPGDCYP2C19ALDH1A1 | |
| SCHEMBL8715073 | 0.75 | TP53 (0.40) | KDM4ECYP1A2HPGDCYP2C19ALDH1A1 | |
| SCHEMBL3050070 | 0.73 | MAPT (0.50) | KDM4ECYP1A2HPGDCYP2C19ALDH1A1 | |
| SCHEMBL29124061 | 0.70 | CDK5 (0.47) | KDM4ECYP1A2HPGDCYP2C19ALDH1A1 | |
| SCHEMBL7426931 | 0.70 | NPC1 (0.53) | KDM4EALDH1A1MAPT | |
| SCHEMBL1287805 | 0.69 | CYP11B1 (0.47) | KDM4ECYP1A2HPGDCYP2C19ALDH1A1 | |
| SCHEMBL8713911 | 0.69 | ANPEP (0.44) | KDM4ECYP1A2HPGDCYP2C19ALDH1A1 | |
| Sulfuric Acid SCHEMBL8944460 | 0.68 | PKM (0.43) | KDM4ECYP1A2HPGDCYP2C19ALDH1A1 | |
| Hydrochloric Acid SCHEMBL8717493 | 0.68 | ANPEP (0.43) | KDM4ECYP1A2HPGDCYP2C19ALDH1A1 | |
| SCHEMBL582334 | 0.66 | NOTUM (0.46) | KDM4ECYP1A2HPGDCYP2C19ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5817654-A | STIMULATE GROWTH HORMONES | NOVO NORDISK A/S (DK) | 1998-10-06 | — | — | US | disclosed |
| EP-0777668-A1 | NOVEL N-SUBSTITUTED NAPHTHOFUSED LACTAMS | NOVO NORDISK A/S (DK) | 1997-06-11 | — | — | EP | disclosed |
| WO-1996005195-A1 | NOVEL N-SUBSTITUTED NAPHTHOFUSED LACTAMS | NOVO NORDISK A/S (DK) | 1996-02-22 | — | — | WO | disclosed |