Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 3/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.47 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.47 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.45 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3050070 | 0.90 | MAPT (0.50) | CYP2C19CYP2C9KDM4ECYP1A2HPGD | |
| Sulfuric Acid SCHEMBL8944460 | 0.89 | PKM (0.43) | CYP2C19CYP2C9KDM4ECYP1A2HPGD | |
| SCHEMBL29124061 | 0.84 | CDK5 (0.47) | CYP2C19KDM4ECYP1A2HPGDSIRT1 | |
| SCHEMBL8944299 | 0.77 | AHR (0.46) | MAPTCDK5CDK5R1PKMKIF11 | |
| SCHEMBL8714752 | 0.76 | KDM4E (0.41) | CYP2C19CYP2C9KDM4ECYP1A2HPGD | |
| SCHEMBL1287805 | 0.75 | CYP11B1 (0.47) | CYP2C19CYP2C9KDM4ECYP1A2HPGD | |
| SCHEMBL15801195 | 0.75 | PNMT (0.45) | CYP2C9KDM4ECYP1A2HPGDHSD17B10 | |
| SCHEMBL8715073 | 0.74 | TP53 (0.40) | CYP2C19CYP2C9KDM4ECYP1A2HPGD | |
| SCHEMBL8713911 | 0.74 | ANPEP (0.44) | CYP2C19CYP2C9KDM4ECYP1A2HPGD | |
| Hydrochloric Acid SCHEMBL8717493 | 0.73 | ANPEP (0.43) | CYP2C19CYP2C9KDM4ECYP1A2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3489215-A1 | PROCESS FOR PRODUCING ORGANIC COMPOUND | Kaneka Corporation (JP) | 2019-05-29 | — | — | EP | disclosed |
| EP-0724440-A4 | DI- AND TETRA-HYDROBENZO F]QUINOLIN-3-ONES | SMITHKLINE BEECHAM CORP (US) | 1996-11-20 | — | — | EP | disclosed |
| EP-0724440-A1 | DI- AND TETRA-HYDROBENZO F]QUINOLIN-3-ONES | SMITHKLINE BEECHAM CORPORATION (US) | 1996-08-07 | — | — | EP | disclosed |
| WO-1995005821-A1 | DI- AND TETRA-HYDROBENZO[F]QUINOLIN-3-ONES | SMITHKLINE BEECHAM CORPORATION (US) | 1995-03-02 | — | — | WO | disclosed |