Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.69 |
| ▸ | MEN1 | O00255 | 5/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.69 |
| ▸ | MAPT | P10636 | 4/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.69 |
| ▸ | HTT | P42858 | 2/20 | 0.69 |
| ▸ | CRHBP | P24387 | 1/20 | 0.69 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.69 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | BLM | P54132 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | THRA | P10827 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30821556 | 0.84 | KMT2A (0.65) | KMT2AMEN1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL8710657 | 0.84 | MAPT (0.59) | KMT2AMEN1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL28012109 | 0.77 | KMT2A (0.68) | KMT2AMEN1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL7748143 | 0.77 | MAPK10 (0.65) | KMT2AMEN1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL22348661 | 0.77 | NPC1 (0.72) | KMT2AMEN1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL13561110 | 0.76 | MAPT (0.76) | KMT2AMEN1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL8870819 | 0.76 | RAB9A (0.64) | KMT2AMEN1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL8711130 | 0.76 | MEN1 (0.86) | KMT2AMEN1ALDH1A1MAPTHTT | |
| SCHEMBL24233277 | 0.75 | SMN1; SMN2 (0.70) | KMT2AMEN1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL27771294 | 0.75 | KMT2A (0.77) | KMT2AMEN1ALDH1A1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5728835-A | HYPOTENSIVE AGENTS; ANTIISCHEMIC AGENTS | TOA EIYO, LTD. (JP) | 1998-03-17 | — | — | US | disclosed |
| EP-0661266-A1 | Substituted cyclic amine compounds as 5HT2 antagonists | TOA EIYO LTD. (JP) | 1995-07-05 | — | — | EP | disclosed |