Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FTO | Q9C0B1 | 8/20 | 0.64 |
| ▸ | MAPT | P10636 | 5/20 | 0.64 |
| ▸ | MEN1 | O00255 | 5/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.64 |
| ▸ | HTT | P42858 | 2/20 | 0.64 |
| ▸ | RECQL | P46063 | 2/20 | 0.64 |
| ▸ | BLM | P54132 | 2/20 | 0.64 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.64 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.64 |
| ▸ | HPGD | P15428 | 2/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.64 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.52 |
| ▸ | GNG2 | P59768 | 1/20 | 0.52 |
| ▸ | GNB1 | P62873 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8718064 | 0.99 | FTO (0.63) | FTOMAPTMEN1KMT2ATDP1 | |
| SCHEMBL10863851 | 0.90 | FTO (0.61) | FTOMAPTMEN1KMT2ATDP1 | |
| SCHEMBL8417782 | 0.87 | FTO (0.70) | FTOMAPTMEN1KMT2ATDP1 | |
| SCHEMBL10863708 | 0.87 | FTO (0.57) | FTOMAPTMEN1KMT2ATDP1 | |
| SCHEMBL3510722 | 0.86 | FTO (0.68) | FTOMAPTMEN1KMT2ATDP1 | |
| SCHEMBL499201 | 0.86 | FTO (0.68) | FTOMAPTMEN1KMT2ATDP1 | |
| SCHEMBL4838173 | 0.86 | FTO (0.68) | FTOMAPTMEN1KMT2ATDP1 | |
| SCHEMBL7973207 | 0.85 | FTO (0.58) | FTOMAPTMEN1KMT2ATDP1 | |
| SCHEMBL3923505 | 0.85 | FTO (0.58) | FTOMAPTMEN1KMT2ATDP1 | |
| Hydrochloric Acid SCHEMBL9650959 | 0.85 | FTO (0.67) | FTOMAPTMEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750413-A | FLUORESCENT MARKERS FOR CYCLOSPORINS | ABBOTT LABORATORIES | 1998-05-12 | — | — | US | disclosed |
| US-5489668-A | DERIVATIVES LABELED WITH DETECTABLE FLUORESCEIN MOIETY FOR USE AS TRACERS | ABBOTT LABORATORIES (US) | 1996-02-06 | — | — | US | disclosed |
| EP-0473961-A2 | Immunoassay reagents and method for determining cyclosporine | ABBOTT LABORATORIES (US) | 1992-03-11 | — | — | EP | disclosed |
| EP-0201751-A2 | 4'-aminomethyfluorescein derivatives for use in fluorescence polarization immunoassys | ABBOTT LABORATORIES (US) | 1986-11-20 | — | — | EP | disclosed |