SCHEMBL499201

SCHEMBL499201

NCc1c(O)ccc2c1Oc1cc(O)ccc1C21OC(=O)c2ccccc21

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FTO Q9C0B1 8/20 0.68
MAPT P10636 5/20 0.68
MEN1 O00255 5/20 0.68
KMT2A Q03164 5/20 0.68
TDP1 Q9NUW8 4/20 0.68
HTT P42858 2/20 0.68
RECQL P46063 2/20 0.68
BLM P54132 2/20 0.68
PRMT1 Q99873 2/20 0.68
ACE2 Q9BYF1 2/20 0.68
HPGD P15428 2/20 0.68
CYP2C19 P33261 1/20 0.68
SMAD3 P84022 1/20 0.68
GNG2 P59768 1/20 0.55
GNB1 P62873 1/20 0.55
LMNA P02545 4/20 0.52
GPR55 Q9Y2T6 2/20 0.52
POLB P06746 2/20 0.52
ALOX12 P18054 2/20 0.52
NPSR1 Q6W5P4 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL3996680 0.99 FTO (0.67) FTOMAPTMEN1KMT2ATDP1
Hydrochloric Acid SCHEMBL9650959 0.99 FTO (0.67) FTOMAPTMEN1KMT2ATDP1
SCHEMBL6812913 0.92 FTO (0.65) FTOMAPTMEN1KMT2ATDP1
SCHEMBL8417782 0.90 FTO (0.70) FTOMAPTMEN1KMT2ATDP1
SCHEMBL3510722 0.89 FTO (0.68) FTOMAPTMEN1KMT2ATDP1
SCHEMBL4838173 0.89 FTO (0.68) FTOMAPTMEN1KMT2ATDP1
SCHEMBL7212008 0.89 GNG2 (0.69) FTOMAPTMEN1KMT2ATDP1
SCHEMBL78588 0.87 FTO (0.53) FTOMAPTMEN1KMT2ATDP1
SCHEMBL5066567 0.86 FTO (0.74) FTOMAPTMEN1KMT2ATDP1
SCHEMBL8714832 0.86 FTO (0.64) FTOMAPTMEN1KMT2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 466 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1810976-B1 BENZONAPHTHACENEGLYCOSIDE DERIVATIVE AND USE THEREOF FUJIFILM CORP (JP) 2014-08-27 EP claimed
US-20080027144-A1 Benzonaphthacene Glycoside Derivative and Use Thereof FUJIFILM CORPORATION (JP) 2008-01-31 US claimed
EP-1882938-A2 Method and apparatus for the fast determination of deoxynivalenol in a cereal-based matrix Barilla G. e R. Fratelli S.p.A. (IT) 2008-01-30 EP claimed
WO-2007122602-A1 A METHOD AND SYSTEM FOR MEASURING MEMBRANE POTENTIAL BASED ON FLUORESCENCE POLARIZATION SENG ENTERPRISES LTD. (CY) 2007-11-01 WO claimed
US-20070254276-A1 Method and system for measuring membrane potential based on fluorescence polarization SENG ENTERPRISES LTD. (CY) 2007-11-01 US claimed
EP-1810976-A1 BENZONAPHTHACENEGLYCOSIDE DERIVATIVE AND USE THEREOF FUJIFILM Corporation (JP) 2007-07-25 EP claimed
US-6794158-B2 FLUORESCENT PROBE FOR USE AS DIAGNOSTIC TOOL IN MONITORING PREFERENTIAL ENZYME ACTIVITY BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. 2004-09-21 US claimed
US-20030082665-A1 Fluorescence polarization assay BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. 2003-05-01 US claimed
WO-2002082082-A2 FLUORESCENCE POLARIZATION ASSAY BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) 2002-10-17 WO claimed
EP-0702689-A4 HAPTENS, TRACERS, IMMUNOGENS AND ANTIBODIES FOR 3-PHENYL-1-ADAMANTANEACETIC ACIDS ABBOTT LAB (US) 1997-10-22 EP claimed
WO-1993020074-A1 HAPTENS, TRACERS, IMMUNOGENS AND ANTIBODIES FOR ACRIDINE-9-CARBOXYLIC ACIDS ABBOTT LABORATORIES (US) 1993-10-14 WO claimed
EP-0279213-B1 FLUORESCENCE POLARIZATION IMMUNOASSAY FOR AMPHETAMINE/METHAMPHETAMINE ABBOTT LABORATORIES (US) 1992-10-21 EP claimed
US-5145791-A Immunology ABBOTT LABORATORIES (US) 1992-09-08 US claimed
US-5145790-A Immunoassay, fluorescein derivative ABBOTT LABORATORIES (US) 1992-09-08 US claimed
US-5096838-A Fluorescent tracers for detection of barbiturates and for antiserums ABBOTT LABORATORIES (US) 1992-03-17 US claimed
EP-0455058-A2 Reagents and method for detecting polychlorinated biphenyls ABBOTT LABORATORIES (US) 1991-11-06 EP claimed
US-4868132-A BINDING TO A FLUORESCEIN TYPE TRACER, PRETREATMENT WITH PERIODATE ABBOTT LABORATORIES (US) 1989-09-19 US claimed
EP-0252404-A2 5-Hydroxy-3-indoleacetic acid fluorescence polarization immunoassay ABBOTT LABORATORIES (US) 1988-01-13 EP claimed
EP-0252405-A2 3-methoxy-4-hydroxyphenylglycol fluorescence polarization immunoassay ABBOTT LABORATORIES (US) 1988-01-13 EP claimed
EP-0201751-A2 4'-aminomethyfluorescein derivatives for use in fluorescence polarization immunoassys ABBOTT LABORATORIES (US) 1986-11-20 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080027144-A1 Benzonaphthacene Glycoside Derivative and Use Thereof SORD, PSAT1, SBDS FTO 645/4885MAPT 1873/4885MEN1 2746/4885
US-20030082665-A1 Fluorescence polarization assay EPHX1, EPHX2, LTA4H FTO 539/4885MAPT 4854/4885MEN1 3476/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.