Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP1 | P22413 | 3/20 | 0.57 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.55 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.55 |
| ▸ | EGFR | P00533 | 2/20 | 0.51 |
| ▸ | GSK3A | P49840 | 2/20 | 0.51 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.51 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.51 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.48 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.48 |
| ▸ | ABL1 | P00519 | 1/20 | 0.47 |
| ▸ | ABL2 | P42684 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL338780 | 0.88 | POLB (0.60) | ENPP1P2RY1POLBABCB1GSK3A | |
| SCHEMBL7644531 | 0.86 | SLC29A1 (0.56) | ENPP1P2RY1POLBSLC29A1ADORA3 | |
| SCHEMBL338677 | 0.86 | POLB (0.57) | ENPP1P2RY1POLBABCB1EGFR | |
| SCHEMBL6423125 | 0.85 | ABCB1 (0.76) | P2RY1ABCB1EGFRGSK3ARPS6KA3 | |
| SCHEMBL7896308 | 0.84 | SLC29A1 (0.57) | ENPP1P2RY1SLC29A1 | |
| SCHEMBL7896654 | 0.84 | POLB (0.58) | POLBSLC29A1GSK3ARPS6KA3MAPK14 | |
| SCHEMBL7040477 | 0.82 | SLC29A1 (0.57) | SLC29A1ADORA3 | |
| SCHEMBL8623380 | 0.81 | POLB (0.65) | ENPP1P2RY1POLBADORA1 | |
| SCHEMBL3259692 | 0.81 | POLB (0.65) | ENPP1P2RY1POLBADORA1 | |
| SCHEMBL159558 | 0.81 | POLB (0.56) | ENPP1P2RY1POLBABCB1GSK3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0639582-B1 | Polynucleotide assay reagent and method | ANTIVIRALS INC (US) | 1998-09-16 | — | — | EP | disclosed |
| US-5470974-A | Uncharged polynucleotide-binding polymers | NEU-GENE DEVELOPMENT GROUP (US) | 1995-11-28 | — | — | US | disclosed |
| EP-0215942-B1 | POLYNUCLEOTIDE ASSAY REAGENT AND METHOD | ANTIVIRALS INC (US) | 1995-07-12 | — | — | EP | disclosed |
| EP-0639582-A2 | Polynucleotide assay reagent and method | ANTIVIRALS INC. (US) | 1995-02-22 | — | — | EP | disclosed |
| US-5217866-A | Polynucleotide assay reagent and method | ANTI-GENE DEVELOPMENT GROUP (US) | 1993-06-08 | — | — | US | disclosed |
| EP-0216860-B1 | STEREOREGULAR POLYNUCLEOTIDE-BINDING POLYMERS | SUMMERTON, James (US) | 1992-10-28 | — | — | EP | disclosed |
| US-5142047-A | Morpholino nucleosides for blocking targeted genetic sequence | ANTI-GENE DEVELOPMENT GROUP (US) | 1992-08-25 | — | — | US | disclosed |
| EP-0216860-A4 | STEREOREGULAR POLYNUCLEOTIDE-BINDING POLYMERS. | SUMMERTON JAMES (US) | 1989-02-22 | — | — | EP | disclosed |
| EP-0215942-A4 | POLYNUCLEOTIDE ASSAY REAGENT AND METHOD. | SUMMERTON JAMES | 1988-08-23 | — | — | EP | disclosed |
| EP-0216860-A1 | STEREOREGULAR POLYNUCLEOTIDE-BINDING POLYMERS. | SUMMERTON JAMES (US) | 1987-04-08 | — | — | EP | disclosed |
| EP-0215942-A1 | POLYNUCLEOTIDE ASSAY REAGENT AND METHOD. | SUMMERTON JAMES | 1987-04-01 | — | — | EP | disclosed |
| WO-1986005518-A1 | STEREOREGULAR POLYNUCLEOTIDE-BINDING POLYMERS | SUMMERTON JAMES | 1986-09-25 | — | — | WO | disclosed |
| WO-1986005519-A1 | POLYNUCLEOTIDE ASSAY REAGENT AND METHOD | SUMMERTON JAMES | 1986-09-25 | — | — | WO | disclosed |