Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.65 |
| ▸ | ENPP1 | P22413 | 3/20 | 0.64 |
| ▸ | P2RY1 | P47900 | 2/20 | 0.64 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
| ▸ | DTYMK | P23919 | 2/20 | 0.51 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.50 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.50 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.50 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.50 |
| ▸ | LDHA | P00338 | 1/20 | 0.50 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.50 |
| ▸ | FBP1 | P09467 | 1/20 | 0.50 |
| ▸ | SRC | P12931 | 1/20 | 0.50 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.50 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.50 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.50 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8623380 | 1.00 | POLB (0.65) | POLBENPP1P2RY1HIF1ADTYMK | |
| SCHEMBL9233212 | 0.94 | POLB (0.59) | POLBENPP1P2RY1HIF1ADTYMK | |
| SCHEMBL3470715 | 0.90 | POLB (0.63) | POLBENPP1P2RY1HIF1ADTYMK | |
| SCHEMBL4625882 | 0.89 | POLB (0.62) | POLBENPP1P2RY1HIF1ADTYMK | |
| SCHEMBL23982376 | 0.89 | POLB (0.52) | POLBENPP1P2RY1PDE4DPDE3A | |
| SCHEMBL1889395 | 0.89 | POLB (0.64) | POLBENPP1P2RY1HIF1APDE4D | |
| SCHEMBL8058699 | 0.89 | POLB (0.64) | POLBENPP1P2RY1HIF1ADTYMK | |
| SCHEMBL5362841 | 0.88 | POLB (0.51) | POLBENPP1P2RY1PDE4DPDE3A | |
| SCHEMBL6833492 | 0.88 | POLB (0.66) | POLBENPP1P2RY1HIF1ADTYMK | |
| SCHEMBL5361698 | 0.88 | POLB (0.51) | POLBENPP1P2RY1PDE4DPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9718855-B2 | Nucleosides and oligonucleotides for studies on reversal of cytotoxic and mutagenic damage of DNA and as diagnostics tools | CHEMGENES CORPORATION (US) | 2017-08-01 | — | — | US | disclosed |
| US-20140350234-A1 | Nucleosides and Oligonucleotides for Studies on Reversal of Cytotoxic and Mutagenic Damage of DNA and as Diagnostics Tools | CHEMGENES CORPORATION (US) | 2014-11-27 | — | — | US | disclosed |
| US-8785619-B1 | Nucleosides and oligonucleotides for studies on reversal of cytotoxic and mutagenic damage of DNA potential diagnostics tools | CHEMGENES CORPORATION (US) | 2014-07-22 | — | — | US | disclosed |
| US-20100028894-A1 | Photographic Determination of Analytes | BASECLICK GMBH (DE) | 2010-02-04 | — | — | US | disclosed |
| EP-2092079-A1 | PHOTOGRAPIC DETERMINATION OF ANALYTES | baseclick GmbH (DE) | 2009-08-26 | — | — | EP | disclosed |
| US-20090087857-A1 | Molecular Beacons for DNA-Photography | BASECLICK GMBH (DE) | 2009-04-02 | — | — | US | disclosed |
| EP-2013363-A1 | MOLECULAR BEACONS FOR DNA-PHOTOGRAPHY | BASF SE (DE) | 2009-01-14 | — | — | EP | disclosed |
| WO-2008055679-A1 | PHOTOGRAPIC DETERMINATION OF ANALYTES | BASECLICK GMBH (DE) | 2008-05-15 | — | — | WO | disclosed |
| WO-2007128430-A1 | MOLECULAR BEACONS FOR DNA-PHOTOGRAPHY | BASF SE (DE) | 2007-11-15 | — | — | WO | disclosed |
| US-7169765-B1 | Acyl deoxyribonucleoside derivatives and uses thereof | WELLSTAT THERAPEUTICS CORPORATION (US) | 2007-01-30 | — | — | US | disclosed |
| US-6306834-B1 | METHODS OF TREATING OR PREVENTING RADIATION, MUTAGEN AND SUNLIGHT-INDUCED BIOLOGICAL DAMAGE, METHODS FOR IMPROVING WOUND HEALING AND TISSUE REPAIR, COMPRISING ADMINISTERING THE COMPOSITIONS OF THE PRESENT INVENTION TO AN ANIMAL. | PRO-NEURON, INC. | 2001-10-23 | — | — | US | disclosed |
| US-6297222-B1 | TREATING OR PREVENTING RADIATION, MUTAGEN AND SUNLIGHT-INDUCED BIOLOGICAL DAMAGE, AND METHODS FOR IMPROVING WOUND HEALING AND TISSUE REPAIR | PRO-NEURON, INC. | 2001-10-02 | — | — | US | disclosed |
| US-6103701-A | ADMINISTERING COMPOSITIONS COMPRISING ACYL DERIVATIVES OF 2'-DEOXYRIBONUCLEOSIDES; FOR IMPROVING WOUND HEALING AND TISSUE REPAIR | VON BORSTEL REID WARREN (US) | 2000-08-15 | — | — | US | disclosed |
| US-6020322-A | Acyl deoxyribonucleoside derivatives and uses thereof | PRO-NEURON, INC. (US) | 2000-02-01 | — | — | US | disclosed |
| US-5756704-A | Nucleosides and nucleoside derivatives containing enzymatically cleavable protecting groups | BOEHRINGER MANNHEIM GMBH (DE) | 1998-05-26 | — | — | US | disclosed |
| US-5677441-A | Nucleosides, nucleotides and oligonucleotides containing enzymatically cleavable protecting groups | BOEHRINGER MANNHEIM GMBH (DE) | 1997-10-14 | — | — | US | disclosed |
| EP-0355131-B1 | ACYL DEOXYRIBONUCLEOSIDE DERIVATIVES AND USES THEREOF | PRO NEURON INC (US) | 1996-09-04 | — | — | EP | disclosed |
| EP-0712629-A1 | Acyl deoxyribonucleoside derivatives and uses thereof | PRO-NEURON, INC. (US) | 1996-05-22 | — | — | EP | disclosed |
| EP-0355131-A1 | ACYL DEOXYRIBONUCLEOSIDE DERIVATIVES AND USES THEREOF | PRO-NEURON, INC. (US) | 1990-02-28 | — | — | EP | disclosed |
| US-4078139-A | Process for deoxygenating secondary alcohols | SCHERING CORPORATION (US) | 1978-03-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140350234-A1 | Nucleosides and Oligonucleotides for Studies on Reversal of Cytotoxic and Mutagenic Damage of DNA and as Diagnostics Tools | UNG, OGG1, ADAR | POLB 7/4885ENPP1 197/4885P2RY1 2422/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.