Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | ENPP1 | P22413 | 3/20 | 0.56 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.56 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.55 |
| ▸ | GSK3A | P49840 | 2/20 | 0.52 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.52 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.52 |
| ▸ | EGFR | P00533 | 1/20 | 0.48 |
| ▸ | CHKA | P35790 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL338780 | 0.89 | POLB (0.60) | POLBENPP1P2RY1ABCB1GSK3A | |
| SCHEMBL8714855 | 0.86 | ENPP1 (0.57) | POLBENPP1P2RY1ABCB1GSK3A | |
| SCHEMBL8623380 | 0.84 | POLB (0.65) | POLBENPP1P2RY1HIF1A | |
| SCHEMBL3259692 | 0.84 | POLB (0.65) | POLBENPP1P2RY1HIF1A | |
| SCHEMBL337873 | 0.84 | ABCB1 (0.75) | P2RY1ABCB1GSK3ARPS6KA3MAPK14 | |
| SCHEMBL18817976 | 0.83 | TYMP (0.58) | POLBENPP1P2RY1CHKA | |
| SCHEMBL3470715 | 0.83 | POLB (0.63) | POLBENPP1P2RY1HIF1A | |
| SCHEMBL439242 | 0.82 | POLB (0.67) | POLBENPP1P2RY1HIF1A | |
| SCHEMBL10021398 | 0.82 | POLB (0.67) | POLBENPP1P2RY1HIF1A | |
| SCHEMBL16359945 | 0.82 | POLB (0.67) | POLBENPP1P2RY1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8097711-B2 | nucleoside monomers protected with thioether substituted aryl carbonate protecting groups; oligonucleotides, using such protected nucleoside monomer monomers, as well as nucleic acids | AGILENT TECHNOLOGIES, INC. (US) | 2012-01-17 | — | — | US | disclosed |
| US-20080146787-A1 | Thioether substituted aryl carbonate protecting groups | AGILENT TECHNOLOGIES, INC. | 2008-06-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080146787-A1 | Thioether substituted aryl carbonate protecting groups | NSUN2, NSUN3, TRDMT1 | POLB 222/4885ENPP1 419/4885P2RY1 1062/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.