Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.38 |
| ▸ | ACP3 | P15309 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.34 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL840826 | 0.86 | ESR1 (0.46) | ESR1TSHRACHEGAAADRA2A | |
| SCHEMBL1033574 | 0.85 | GABRA1 (0.39) | ESR1TSHRADRB2SLC6A2GABRA1 | |
| SCHEMBL11294903 | 0.77 | ESR1 (0.46) | ESR1TSHRACHEGAAADRA2A | |
| SCHEMBL28656941 | 0.74 | ESR1 (0.43) | ESR1TSHRACHEGAAADRA2A | |
| SCHEMBL19003107 | 0.74 | ESR1 (0.48) | ESR1TSHRACHEGAAADRA2A | |
| SCHEMBL3195038 | 0.73 | GABRA1 (0.37) | ESR1TSHRADRB2SLC6A2GABRA1 | |
| SCHEMBL38664948 | 0.73 | ESR1 (0.52) | ESR1TSHRACHEGAAADRA2A | |
| SCHEMBL7783992 | 0.73 | ESR1 (0.52) | ESR1TSHRACHEGAAADRA2A | |
| SCHEMBL4089214 | 0.72 | TSHR (0.33) | TSHRSLC6A2SLC6A4SLC6A3GABRA1 | |
| SCHEMBL7614292 | 0.72 | ESR1 (0.42) | ESR1TSHRACHEGAAADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5726336-A | REACTING A BENZENE COMPOUND WITH A VINYLCHLOROSILANE COMPOUND IN THE PRESENCE OF A LEWIS ACID CATALYST; INTERMEDIATES FOR SILICONE POLYMERS USEFUL AS EMULSIONS, GREASES, ADHESIVES, SEALANTS, COATINGS, IN AUTOMOTIVE AND ENGINEERING FIELDS | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 1998-03-10 | — | — | US | disclosed |