Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 5/20 | 0.49 |
| ▸ | POLB | P06746 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5684514 | 0.86 | LTA4H (0.62) | LTA4HPOLBNPC1RAB9AMAPT | |
| SCHEMBL8710875 | 0.81 | LTA4H (0.49) | LTA4HPOLBNPC1RAB9AALDH1A1 | |
| Hydrochloric Acid SCHEMBL8107928 | 0.80 | LTA4H (0.58) | LTA4HPOLBNPC1RAB9AMAPT | |
| Hydrochloric Acid SCHEMBL8711512 | 0.80 | LTA4H (0.49) | LTA4HPOLBNPC1RAB9AALDH1A1 | |
| SCHEMBL8107892 | 0.79 | LTA4H (0.76) | LTA4HPOLBNPC1RAB9A | |
| Hydrochloric Acid SCHEMBL8107931 | 0.77 | LTA4H (0.58) | LTA4HPOLBNPC1RAB9AMAPT | |
| SCHEMBL8107445 | 0.71 | LTA4H (0.62) | LTA4HPOLBNPC1RAB9AALDH1A1 | |
| Hydrochloric Acid SCHEMBL8107416 | 0.70 | LTA4H (0.61) | LTA4HPOLBNPC1RAB9AALDH1A1 | |
| SCHEMBL8765739 | 0.68 | LTA4H (0.69) | LTA4HL3MBTL1 | |
| SCHEMBL8641130 | 0.68 | LTA4H (0.56) | LTA4HPOLBNPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998040354-A1 | LTA4 HYDROLASE INHIBITORS | G.D. SEARLE & CO. (US) | 1998-09-17 | — | — | WO | claimed |
| WO-1998040354-A1 | LTA4 HYDROLASE INHIBITORS | G.D. SEARLE & CO. (US) | 1998-09-17 | — | — | WO | disclosed |