Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7139744 | 0.81 | LTA4H (1.00) | LTA4H | |
| SCHEMBL7132986 | 0.81 | LTA4H (1.00) | LTA4HL3MBTL1 | |
| SCHEMBL7137987 | 0.80 | LTA4H (0.98) | LTA4HL3MBTL1 | |
| SCHEMBL10876248 | 0.80 | LTA4H (0.53) | LTA4HL3MBTL1 | |
| SCHEMBL2479744 | 0.76 | OPRK1 (0.55) | LTA4H | |
| SCHEMBL7646541 | 0.76 | LTA4H (0.60) | LTA4HL3MBTL1 | |
| SCHEMBL7139573 | 0.75 | LTA4H (1.00) | LTA4HL3MBTL1 | |
| SCHEMBL8061292 | 0.75 | LTA4H (0.65) | LTA4H | |
| SCHEMBL7139497 | 0.74 | LTA4H (1.00) | LTA4H | |
| SCHEMBL5176477 | 0.74 | LTA4H (0.74) | LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786992-A2 | LTA 4? HYDROLASE INHIBITOR PHARMACEUTICAL COMPOSITIONS AND METHODS OF USE | G.D. SEARLE & CO. (US) | 1997-08-06 | — | — | EP | disclosed |
| WO-1996010999-A2 | LTA4 HYDROLASE INHIBITOR PHARMACEUTICAL COMPOSITIONS AND METHODS OF USE | G.D. SEARLE & CO. (US) | 1996-04-18 | — | — | WO | disclosed |