Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR4 | P61073 | 12/20 | 0.68 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.68 |
| ▸ | MEN1 | O00255 | 1/20 | 0.68 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.68 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.68 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.68 |
| ▸ | CCR2 | P41597 | 1/20 | 0.68 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.68 |
| ▸ | BLM | P54132 | 1/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.68 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | PLK4 | O00444 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1578113 | 0.98 | SIGMAR1 (0.66) | CXCR4HRH3MEN1CHRM2CHRM1 | |
| SCHEMBL15651459 | 0.91 | CXCR4 (0.77) | CXCR4HRH3MEN1CHRM2CHRM1 | |
| SCHEMBL1259387 | 0.90 | CXCR4 (0.81) | CXCR4HRH3MEN1CHRM2CHRM1 | |
| Bromide SCHEMBL1257550 | 0.88 | CXCR4 (0.78) | CXCR4HRH3MEN1CHRM2CHRM1 | |
| Hydrochloric Acid SCHEMBL5573232 | 0.86 | CXCR4 (0.78) | CXCR4HRH3MEN1CHRM2CHRM1 | |
| SCHEMBL15043631 | 0.84 | CXCR4 (0.92) | CXCR4HRH3MEN1CHRM2CHRM1 | |
| SCHEMBL14640062 | 0.84 | CXCR4 (0.78) | CXCR4HRH3MEN1CHRM2CHRM1 | |
| SCHEMBL10690328 | 0.83 | LMNA (0.80) | CXCR4HRH3SIGMAR1ALDH1A1LMNA | |
| SCHEMBL7856149 | 0.83 | SIGMAR1 (0.61) | CXCR4HRH3MEN1CHRM2CHRM1 | |
| SCHEMBL14478352 | 0.83 | SIGMAR1 (0.53) | CXCR4HRH3MEN1CHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0296522-B1 | Functionalized polyamine chelants and rhodium complexes thereof and process for their preparation | DOW CHEMICAL CO (US) | 1996-09-25 | — | — | EP | claimed |
| US-5489425-A | RHODIUM COMPLEXES ATTACHED TO ANTIBODY OR FAB FRAGMENTS FOR THERAPY OR MEDICAL DIAGNOSIS; ANTICARCINOGENIC AND -TUMOR AGENTS; RADIOLOGY; IMMUNOLOGY | THE DOW CHEMICAL COMPANY (US) | 1996-02-06 | — | — | US | claimed |
| EP-0353450-B1 | Macrocyclic bifunctional chelants, complexes thereof and their antibody conjugates | DOW CHEMICAL CO (US) | 1995-03-29 | — | — | EP | claimed |
| US-5284644-A | Anticancer agent; therapy and diagnosis | DOW CHEMICAL COMPANY, THE | 1994-02-08 | — | — | US | claimed |
| US-5006643-A | Reacting aminofunctional chelates with thiophosgene | THE DOW CHEMICAL COMPANY (US) | 1991-04-09 | — | — | US | claimed |
| US-4994560-A | Radiotherapy, diagnosis | THE DOW CHEMICAL COMPANY (US) | 1991-02-19 | — | — | US | claimed |
| WO-1990007342-A1 | PROCESS FOR PREPARING ISOTHIOCYANATO FUNCTIONALIZED METAL COMPLEXES | THE DOW CHEMICAL COMPANY (US) | 1990-07-12 | — | — | WO | claimed |
| EP-0374947-A1 | Process for preparing isothiocyanato functionalized metal complexes | THE DOW CHEMICAL COMPANY (US) | 1990-06-27 | — | — | EP | claimed |
| EP-0296522-A2 | Functionalized polyamine chelants and rhodium complexes thereof and process for their preparation | THE DOW CHEMICAL COMPANY (US) | 1988-12-28 | — | — | EP | claimed |
| US-5756065-A | DIAGNOSTIC CHELATES FOR ANTIBODIES AND RADIOACTIVE MATERIALS | THE DOW CHEMICAL COMPANY (US) | 1998-05-26 | — | — | US | disclosed |
| US-5652361-A | ANTITUMOR | THE DOW CHEMICAL COMPANY (US) | 1997-07-29 | — | — | US | disclosed |
| EP-0296522-B1 | Functionalized polyamine chelants and rhodium complexes thereof and process for their preparation | DOW CHEMICAL CO (US) | 1996-09-25 | — | — | EP | disclosed |
| US-5489425-A | RHODIUM COMPLEXES ATTACHED TO ANTIBODY OR FAB FRAGMENTS FOR THERAPY OR MEDICAL DIAGNOSIS; ANTICARCINOGENIC AND -TUMOR AGENTS; RADIOLOGY; IMMUNOLOGY | THE DOW CHEMICAL COMPANY (US) | 1996-02-06 | — | — | US | disclosed |
| US-5435990-A | Chelate-antibody complexes, treatment and diagnosis of cancer, tetraazacyclododecane compounds | THE DOW CHEMICAL COMPANY (US) | 1995-07-25 | — | — | US | disclosed |
| US-4994560-A | Radiotherapy, diagnosis | THE DOW CHEMICAL COMPANY (US) | 1991-02-19 | — | — | US | disclosed |
| WO-1990007342-A1 | PROCESS FOR PREPARING ISOTHIOCYANATO FUNCTIONALIZED METAL COMPLEXES | THE DOW CHEMICAL COMPANY (US) | 1990-07-12 | — | — | WO | disclosed |
| EP-0374947-A1 | Process for preparing isothiocyanato functionalized metal complexes | THE DOW CHEMICAL COMPANY (US) | 1990-06-27 | — | — | EP | disclosed |
| EP-0353450-A1 | Macrocyclic bifunctional chelants, complexes thereof and their antibody conjugates | THE DOW CHEMICAL COMPANY (US) | 1990-02-07 | — | — | EP | disclosed |
| WO-1989012631-A1 | MACROCYCLIC BIFUNCTIONAL CHELANTS, COMPLEXES THEREOF AND THEIR ANTIBODY CONJUGATES | THE DOW CHEMICAL COMPANY (US) | 1989-12-28 | — | — | WO | disclosed |
| EP-0296522-A2 | Functionalized polyamine chelants and rhodium complexes thereof and process for their preparation | THE DOW CHEMICAL COMPANY (US) | 1988-12-28 | — | — | EP | disclosed |