Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 12/20 | 0.48 |
| ▸ | MTNR1B | P49286 | 11/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8718574 | 0.69 | MTNR1A (0.42) | MTNR1AMTNR1BSMN1; SMN2 | |
| SCHEMBL7055579 | 0.68 | MTNR1A (0.48) | MTNR1AMTNR1BPOLB | |
| SCHEMBL8717471 | 0.64 | CNR2 (0.40) | MTNR1AMTNR1B | |
| SCHEMBL17949536 | 0.64 | MTNR1A (0.69) | MTNR1AMTNR1B | |
| SCHEMBL8711852 | 0.64 | MTNR1A (0.50) | MTNR1AMTNR1BSMN1; SMN2 | |
| SCHEMBL8136431 | 0.63 | MTNR1A (0.78) | MTNR1AMTNR1B | |
| SCHEMBL7893165 | 0.62 | SMN1; SMN2 (0.52) | MTNR1AMTNR1BSMN1; SMN2 | |
| SCHEMBL8712203 | 0.62 | MTNR1A (0.61) | MTNR1AMTNR1BPOLB | |
| SCHEMBL7056605 | 0.61 | MTNR1A (0.37) | MTNR1AMTNR1B | |
| SCHEMBL8717757 | 0.61 | MTNR1A (0.45) | MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5770610-A | ADMINISTERING R-(+)-N-(2-METHYL-2-(5-METHOXY-6-CHLOROINDOL-3-YL)ETHYL) ACETAMIDE | ELI LILLY AND COMPANY (US) | 1998-06-23 | — | — | US | disclosed |