SCHEMBL8715162

SCHEMBL8715162

CCCCN1c2ccccc2Sc2cc(C=O)ccc21

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 10/20 0.54
PDF Q9HBH1 2/20 0.50
TP53 P04637 2/20 0.49
CYP1A2 P05177 2/20 0.49
CYP2D6 P10635 2/20 0.49
TSHR P16473 2/20 0.49
THPO P40225 2/20 0.49
MTOR P42345 2/20 0.49
SIGMAR1 Q99720 2/20 0.49
SLC22A1 O15245 1/20 0.49
PRNP P04156 1/20 0.49
ADRB2 P07550 1/20 0.49
CHRM2 P08172 1/20 0.49
CHRM4 P08173 1/20 0.49
HTR1A P08908 1/20 0.49
CHRM5 P08912 1/20 0.49
ADRA2A P08913 1/20 0.49
CHRM1 P11229 1/20 0.49
DRD2 P14416 1/20 0.49
ADRA2B P18089 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31174404 0.95 PDF (0.53) KDM1APDFTP53CYP1A2CYP2D6
SCHEMBL29376040 0.92 PDF (0.48) KDM1APDFTP53CYP1A2CYP2D6
SCHEMBL25842328 0.92 PDF (0.48) KDM1APDFTP53CYP1A2CYP2D6
SCHEMBL5115700 0.91 PIM1 (0.55) KDM1ATP53CYP1A2CYP2D6TSHR
SCHEMBL5112085 0.91 PIM1 (0.55) KDM1ATP53CYP1A2CYP2D6TSHR
SCHEMBL27766622 0.88 PDF (0.43) KDM1APDFTP53CYP1A2CYP2D6
SCHEMBL31174406 0.88 PDF (0.43) KDM1APDFTP53CYP1A2CYP2D6
SCHEMBL19746326 0.87 PIM1 (0.48) KDM1ATP53CYP1A2CYP2D6TSHR
SCHEMBL28910968 0.87 KDM1A (0.54) KDM1APDFTP53CYP1A2CYP2D6
SCHEMBL31481617 0.86 ALDH1A1 (0.48) KDM1ATP53CYP1A2CYP2D6SLC22A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117143044-B Fluorescent probe for hydrazine detection and preparation method and application thereof 新乡医学院 2025-01-17 CN claimed
CN-118978541-A Novel BODIPY-based near-infrared ratio type fluorescent probe for targeted detection of endoplasmic reticulum hypochlorous acid and preparation method and application thereof 南京林业大学 2024-11-19 CN claimed
CN-117143044-A Fluorescent probe for hydrazine detection and preparation method and application thereof 新乡医学院 2023-12-01 CN claimed
CN-112694471-B Benzondolium-phenothiazine derivative, and preparation and application thereof 西北师范大学 2023-10-24 CN claimed
CN-112694471-A Benzoindole salt-phenothiazine derivative and preparation and application thereof 西北师范大学 2021-04-23 CN claimed
CN-106699750-B Phenothiazine-triarylpyridine organic yellow-green luminescent compound and preparation and application thereof 江苏师范大学 2019-12-24 CN claimed
CN-121800773-A Fluorescent probe compound with polyarylimidazole modified phenothiazine derivative as core structure, and preparation method and application thereof 黑龙江大学 2026-04-07 CN disclosed
CN-117143044-B Fluorescent probe for hydrazine detection and preparation method and application thereof 新乡医学院 2025-01-17 CN disclosed
CN-117143044-A Fluorescent probe for hydrazine detection and preparation method and application thereof 新乡医学院 2023-12-01 CN disclosed
CN-112694471-B Benzondolium-phenothiazine derivative, and preparation and application thereof 西北师范大学 2023-10-24 CN disclosed
CN-112694471-A Benzoindole salt-phenothiazine derivative and preparation and application thereof 西北师范大学 2021-04-23 CN disclosed
CN-106699750-B Phenothiazine-triarylpyridine organic yellow-green luminescent compound and preparation and application thereof 江苏师范大学 2019-12-24 CN disclosed
CN-101659662-B Undoped red organic electroluminescent material and preparation method and applications thereof UNIV BEIJING 2011-07-27 CN disclosed
CN-101659662-A Undoped red organic electroluminescent material and preparation method and applications thereof UNIV BEIJING 2010-03-03 CN disclosed
US-5830902-A SQUALENE SYNTHASE INHIBITOR YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) 1998-11-03 US disclosed
CN-1177353-A Novel quinuclidine derivatives having tricyclic fused hereto ring YAMANOUCHI PHARMA CO LTD (JP) 1998-03-25 CN disclosed
EP-0812840-A1 NOVEL QUINUCLIDINE DERIVATIVES HAVING TRICYCLIC FUSED HETERO RING YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) 1997-12-17 EP disclosed