Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 7/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HTR1D | P28221 | 1/20 | 0.31 |
| ▸ | HTR1B | P28222 | 1/20 | 0.31 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.31 |
| ▸ | BAX | Q07812 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8900759 | 0.91 | CA4 (0.42) | CA4LTA4HCHRNB2CHRNB4CHRNA3 | |
| SCHEMBL9817929 | 0.76 | LMNA (0.37) | CA4LTA4HCHRNB2CHRNB4CHRNA3 | |
| SCHEMBL8715173 | 0.73 | CA4 (0.42) | CA4LTA4HCHRNB2CHRNB4CHRNA3 | |
| SCHEMBL27884238 | 0.71 | LTA4H (0.40) | CA4LTA4HCHRNB2CHRNB4CHRNA3 | |
| SCHEMBL10883757 | 0.70 | CA4 (0.50) | CA4LTA4HTSHRKCNA3MAOB | |
| SCHEMBL7056924 | 0.66 | — | — | |
| SCHEMBL10879171 | 0.65 | LTA4H (0.43) | CA4LTA4HCHRNB2CHRNB4CHRNA3 | |
| SCHEMBL10880957 | 0.65 | LTA4H (0.41) | CA4LTA4HCHRNB2CHRNB4CHRNA3 | |
| SCHEMBL395207 | 0.64 | CA4 (0.48) | CA4LTA4HTSHRKCNA3LMNA | |
| SCHEMBL394526 | 0.64 | CA4 (0.48) | CA4LTA4HTSHRKCNA3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5744678-A | NICKEL COMPOUND, ORGANOPHOSPHORUS COMPOUND, ORGANOALUMINUM COMPOUND, CARBON-HALOGEN COMPOUNDS; CATALYST SELECTIVITY | NIPPON OIL CO., LTD. (JP) | 1998-04-28 | — | — | US | disclosed |