⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7166778 | 1.00 | ALDH1A1 (0.42) | — | |
| Trifluoroacetic Acid SCHEMBL30657022 | 0.95 | — | — | |
| Trifluoroacetic Acid SCHEMBL7814389 | 0.95 | ALDH1A1 (0.44) | — | |
| Trifluoroacetic Acid SCHEMBL4598430 | 0.95 | — | — | |
| Trifluoroacetic Acid SCHEMBL474 | 0.95 | — | — | |
| Trifluoroacetic Acid SCHEMBL2484766 | 0.95 | ALDH1A1 (0.44) | — | |
| Trifluoroacetic Acid SCHEMBL25297651 | 0.91 | ALDH1A1 (0.42) | — | |
| Trifluoroacetic Acid SCHEMBL21802705 | 0.91 | ALDH1A1 (0.42) | — | |
| Trifluoroacetic Acid SCHEMBL20571142 | 0.91 | — | — | |
| Trifluoroacetic Acid SCHEMBL20541014 | 0.91 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260022130-A1 | HETEROCYCLIC COMPOUNDS AS MONOACYLGLYCEROL LIPASE INHIBITORS | HOFFMANN-LA ROCHE INC. (US) | 2026-01-22 | — | — | US | disclosed |
| US-12281124-B2 | Heterocyclic compounds as monoacylglycerol lipase inhibitors | HOFFMANN-LA ROCHE INC. (US) | 2025-04-22 | — | — | US | disclosed |
| US-20240150373-A1 | HETEROCYCLIC COMPOUNDS AS MONOACYLGLYCEROL LIPASE INHIBITORS | HOFFMANN-LA ROCHE INC. (US) | 2024-05-09 | — | — | US | disclosed |
| US-11802133-B2 | Heterocyclic compounds as monoacylglycerol lipase inhibitors | HOFFMANN-LA ROCHE INC. (US) | 2023-10-31 | — | — | US | disclosed |
| US-20230050901-A1 | HETEROCYCLIC COMPOUNDS AS MONOACYLGLYCEROL LIPASE INHIBITORS | HOFFMANN-LA ROCHE INC. (US) | 2023-02-16 | — | — | US | disclosed |
| CN-106535944-A | Polymeric enkephalin prodrugs | PEG生物制药公司 | 2017-03-22 | — | — | CN | disclosed |
| CN-103370304-A | Sulfonium sulfates, their preparation and use | BASF SE | 2013-10-23 | — | — | CN | disclosed |
| EP-0852565-A4 | SULFUR RECOVERY PROCESS USING SULFUR DEBONDING AGENT | MARATHON OIL CO (US) | 1998-12-02 | — | — | EP | disclosed |
| EP-0852565-A1 | SULFUR RECOVERY PROCESS USING SULFUR DEBONDING AGENT | MARATHON OIL COMPANY (US) | 1998-07-15 | — | — | EP | disclosed |
| US-5736117-A | USING SULFUR DEBONDING AGENT | MARATHON OIL COMPANY (US) | 1998-04-07 | — | — | US | disclosed |
| WO-1997011906-A1 | SULFUR RECOVERY PROCESS USING SULFUR DEBONDING AGENT | MARATHON OIL COMPANY (US) | 1997-04-03 | — | — | WO | disclosed |