Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.75 |
| ▸ | CASR | P41180 | 1/20 | 0.66 |
| ▸ | LMNA | P02545 | 3/20 | 0.62 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | MTOR | P42345 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL924286 | 1.00 | HSD17B10 (0.75) | HSD17B10CASRLMNAEPHX1MEN1 | |
| SCHEMBL15093717 | 1.00 | HSD17B10 (0.75) | HSD17B10CASRLMNAEPHX1MEN1 | |
| SCHEMBL8715641 | 1.00 | HSD17B10 (0.75) | HSD17B10CASRLMNAEPHX1MEN1 | |
| SCHEMBL13500530 | 0.94 | HSD17B10 (0.68) | HSD17B10CASRLMNAEPHX1MEN1 | |
| SCHEMBL13594604 | 0.90 | HSD17B10 (0.68) | HSD17B10CASRLMNAEPHX1MEN1 | |
| SCHEMBL14288556 | 0.90 | HSD17B10 (0.68) | HSD17B10CASRLMNAEPHX1MEN1 | |
| SCHEMBL13923627 | 0.90 | HSD17B10 (0.68) | HSD17B10CASRLMNAEPHX1MEN1 | |
| SCHEMBL10679562 | 0.88 | HSD17B10 (0.66) | HSD17B10CASRLMNAEPHX1MEN1 | |
| SCHEMBL25336459 | 0.86 | MMP9 (0.66) | HSD17B10LMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL247742 | 0.86 | HSD17B10 (0.63) | HSD17B10CASRLMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5728874-A | Anti-HIV achiral polyurea oligomers, a process for creating them, formulations using them, and their use in the treatment of AIDS | MERRELL PHARMACEUTICALS, INC. (US) | 1998-03-17 | — | — | US | disclosed |