Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | HPGD | P15428 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | MMP9 | P14780 | 1/20 | 0.56 |
| ▸ | MMP8 | P22894 | 1/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.56 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.56 |
| ▸ | CASR | P41180 | 1/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2672977 | 1.00 | HSD17B10 (0.63) | HSD17B10MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL249524 | 1.00 | HSD17B10 (0.63) | HSD17B10MEN1KMT2AALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL4459970 | 0.98 | HSD17B10 (0.61) | HSD17B10MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL9718520 | 0.98 | HSD17B10 (0.61) | HSD17B10MEN1KMT2AALDH1A1HPGD | |
| Chloromethane SCHEMBL29855624 | 0.96 | HSD17B10 (0.59) | HSD17B10MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL28210163 | 0.94 | HSD17B10 (0.58) | HSD17B10MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL28305666 | 0.92 | HSD17B10 (0.56) | HSD17B10MEN1KMT2AALDH1A1HPGD | |
| Alcohol SCHEMBL28032632 | 0.92 | MEN1 (0.64) | HSD17B10MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL17571990 | 0.88 | ALDH1A1 (0.61) | HSD17B10MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL28306863 | 0.87 | HSD17B10 (0.51) | HSD17B10MEN1KMT2AALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 195 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116283557-B | Resolution method of S-type and R-type flurbiprofen | 江苏汉邦科技股份有限公司 | 2025-02-25 | — | — | CN | claimed |
| EP-4069691-B1 | SUBSTITUTED TETRAHYDROFURANS AS MODULATORS OF SODIUM CHANNELS | VERTEX PHARMA (US) | 2024-09-18 | — | — | EP | claimed |
| CN-116283557-A | Resolution method of S-type and R-type flurbiprofen | 江苏汉邦科技股份有限公司 | 2023-06-23 | — | — | CN | claimed |
| EP-3364940-B1 | METHOD OF CHROMATOGRAPHIC SEPARATION | PROCTER & GAMBLE (US) | 2019-08-07 | — | — | EP | claimed |
| US-10035759-B2 | Method of chromatographic separation | THE PROCTER & GAMBLE COMPANY (US) | 2018-07-31 | — | — | US | claimed |
| US-20170036994-A1 | METHOD OF CHROMATOGRAPHIC SEPARATION | THE PROCTER & GAMBLE COMPANY | 2017-02-09 | — | — | US | claimed |
| US-8569499-B2 | Process for making trans-1-((1R,3S)-6-chloro-3-phenylindan-1-yl)-3,3-dimethylpiperazine | H. LUNDBECK A/S (DK) | 2013-10-29 | — | — | US | claimed |
| EP-2352721-B1 | NOVEL PROCESS FOR THE PREPARATION OF AMINO ACID DERIVATIVES | UCB PHARMA GMBH (DE) | 2013-03-27 | — | — | EP | claimed |
| EP-1968916-B1 | Process for the separation of optical isomers of the corey lactone | CHINOIN GYOGYSZER ES VEGYESZET (HU) | 2012-07-11 | — | — | EP | claimed |
| EP-1828198-B1 | METHOD FOR SEPARATING OF OPTICALLY PURE THIOPHENE COMPOUNDS USING SIMULATED MOVING BED CHROMATOGRAPHY | SK HOLDINGS CO LTD (KR) | 2011-02-09 | — | — | EP | claimed |
| US-7166587-B2 | Carbamic acid alkyl ester derivatives | HOFFMANN-LA ROCHE INC. (US) | 2007-01-23 | — | — | US | claimed |
| US-20060063746-A1 | 17-carbamoyloxy cortisol derivatives as selective glucocorticoid receptor modulators | MERCK SHARP & DOHME CORP. | 2006-03-23 | — | — | US | claimed |
| EP-1587818-A2 | 17-CARBAMOYLOXY CORTISOL DERIVATIVES AS SELECTIVE GLUCOCORTICOID RECEPTOR MODULATORS | Merck & Co., Inc. (US) | 2005-10-26 | — | — | EP | claimed |
| US-20050075327-A1 | Carbamic acid alkyl ester derivatives | HOFFMAN-LA ROCHE INC. | 2005-04-07 | — | — | US | claimed |
| WO-2004066920-A2 | 17-CARBAMOYLOXY CORTISOL DERIVATIVES AS SELECTIVE GLUCOCORTICOID RECEPTOR MODULATORS | MERCK & CO. INC. (US) | 2004-08-12 | — | — | WO | claimed |
| EP-0865430-B1 | 3-(4-SUBST.-PIPERIDINYL-1)-1-(3,4-DICHLOROPHENYL)PROPYL CARBAMATES AND UREAS AND DERIVATIVES AS NOVEL NEUROKININ ANTAGONISTS | ASTRAZENECA AB (SE) | 2004-03-03 | — | — | EP | claimed |
| US-RE37303-E1 | Imidazole compounds and their therapeutic applications | INSTITUT NATIONAL DEL LA SANTE ET DE LA RECHERCHE MEDICALE (FR) | 2001-07-31 | — | — | US | claimed |
| EP-0865430-A1 | 3-(4-SUBST.-PIPERIDINYL-1)-1-(3,4-DICHLOROPHENYL)PROPYL CARBAMATES AND UREAS AND DERIVATIVES AS NOVEL NEUROKININ ANTAGONISTS | AstraZeneca AB (SE) | 1998-09-23 | — | — | EP | claimed |
| US-5708171-A | HISTAMINE H3-RECEPTOR ANTAGONIST | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) | 1998-01-13 | — | — | US | claimed |
| WO-1997019060-A1 | 3-(4-SUBST.-PIPERIDINYL-1)-1-(3,4-DICHLOROPHENYL)PROPYL CARBAMATES AND UREAS AND DERIVATIVES AS NOVEL NEUROKININ ANTAGONISTS | ZENECA LIMITED (GB) | 1997-05-29 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050075327-A1 | Carbamic acid alkyl ester derivatives | BCHE, CHRM1, ADCY7 | HSD17B10 1009/4885MEN1 1340/4885KMT2A 2212/4885 |
| US-20170036994-A1 | METHOD OF CHROMATOGRAPHIC SEPARATION | AVPR2, SHBG, AVPR1B | HSD17B10 336/4885MEN1 1199/4885KMT2A 4552/4885 |
| US-20060063746-A1 | 17-carbamoyloxy cortisol derivatives as selective glucocorticoid receptor modulators | NR3C1, NR3C2, MC2R | HSD17B10 153/4885MEN1 1772/4885KMT2A 2954/4885 |
| US-10035759-B2 | Method of chromatographic separation | AVPR2, SHBG, AVPR1B | HSD17B10 336/4885MEN1 1199/4885KMT2A 4552/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.