Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8717754 | 0.86 | CYP3A4 (0.41) | CYP3A4L3MBTL1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL6361667 | 0.77 | HPGD (0.32) | — | |
| Hydrochloric Acid SCHEMBL6357067 | 0.62 | CYP3A4 (0.38) | CYP3A4L3MBTL1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL27267867 | 0.62 | CYP3A4 (0.38) | CYP3A4L3MBTL1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL8715936 | 0.62 | CYP3A4 (0.37) | CYP3A4L3MBTL1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL27268509 | 0.61 | NR5A1 (0.30) | — | |
| SCHEMBL6357923 | 0.60 | CYP3A4 (0.40) | CYP3A4L3MBTL1ALDH1A1 | |
| SCHEMBL8712439 | 0.60 | ALDH1A1 (0.40) | CYP3A4L3MBTL1ALDH1A1 | |
| SCHEMBL6903241 | 0.60 | CYP3A4 (0.38) | CYP3A4L3MBTL1ALDH1A1 | |
| SCHEMBL27279270 | 0.60 | CYP3A4 (0.38) | CYP3A4L3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0669346-B1 | Solid catalyst components for olefin polymerization and use thereof | NIPPON OIL CO LTD (JP) | 1998-06-03 | — | — | EP | disclosed |
| EP-0669346-A1 | Solid catalyst components for olefin polymerization and use thereof | NIPPON OIL CO. LTD. (JP) | 1995-08-30 | — | — | EP | disclosed |