SCHEMBL8715754

SCHEMBL8715754

CCCCCCc1cc(C=O)sc1C=O

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 1/20 0.38
EPAS1 Q99814 1/20 0.38
GPR35 Q9HC97 1/20 0.38
ALOX5 P09917 3/20 0.37
MEN1 O00255 1/20 0.37
TP53 P04637 1/20 0.37
CYP3A4 P08684 1/20 0.37
MAPT P10636 1/20 0.37
TYR P14679 1/20 0.37
ALOX15 P16050 1/20 0.37
TSHR P16473 1/20 0.37
HTT P42858 1/20 0.37
KMT2A Q03164 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
NR1H2 P55055 1/20 0.35
NR1H3 Q13133 1/20 0.35
GPR84 Q9NQS5 8/20 0.34
LIPG Q9Y5X9 1/20 0.34
PTGS2 P35354 2/20 0.33
KDM4E B2RXH2 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2714376 1.00 HIF1A (0.38) HIF1AEPAS1GPR35ALOX5MEN1
SCHEMBL13488470 0.85 HIF1A (0.39) HIF1AEPAS1GPR35ALOX5MEN1
SCHEMBL26603205 0.83 HIF1A (0.38) HIF1AEPAS1GPR35ALOX5MEN1
SCHEMBL31513841 0.82 HIF1A (0.37) HIF1AEPAS1GPR35ALOX5MEN1
SCHEMBL16977320 0.82 GPR35 (0.40) HIF1AEPAS1GPR35ALOX5MEN1
SCHEMBL18041179 0.82 HIF1A (0.41) HIF1AEPAS1GPR35ALOX5MEN1
SCHEMBL28096095 0.82 HIF1A (0.41) HIF1AEPAS1GPR35ALOX5MEN1
SCHEMBL18041198 0.82 HIF1A (0.41) HIF1AEPAS1GPR35ALOX5MEN1
SCHEMBL2742443 0.82 GPR84 (0.40) HIF1AEPAS1GPR35ALOX5MEN1
SCHEMBL27845494 0.80 CYP2A6 (0.36) MEN1MAPTKMT2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102781908-A Novel azomethine oligomers SOKEN KAGAKU KK 2012-11-14 CN disclosed
US-20080156369-A1 Active layers utilized in solar cells and fabrication method thereof INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE 2008-07-03 US disclosed
US-5807974-A POLYARYLENEVINYLENE RESIN KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 1998-09-15 US disclosed