Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | ABAT | P80404 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL27861974 | 0.98 | TSHR (0.47) | TSHRALDH1A1NPSR1ABATGAA | |
| SCHEMBL28979912 | 0.78 | SMN1; SMN2 (0.64) | ALDH1A1ABATGAASMN1; SMN2KDM4E | |
| SCHEMBL872298 | 0.76 | ATM (0.42) | TSHRALDH1A1NPSR1GAASMN1; SMN2 | |
| SCHEMBL21163690 | 0.76 | ATM (0.42) | TSHRALDH1A1NPSR1GAASMN1; SMN2 | |
| SCHEMBL7459183 | 0.76 | TSHR (0.40) | TSHRALDH1A1NPSR1GAASMN1; SMN2 | |
| Hippuric Acid SCHEMBL7486 | 0.75 | GAA (0.68) | GAASMN1; SMN2KDM4EMAPTALOX15 | |
| SCHEMBL22030672 | 0.75 | GAA (0.68) | GAASMN1; SMN2KDM4EMAPTALOX15 | |
| Hippuric Acid SCHEMBL428479 | 0.75 | GAA (0.68) | GAASMN1; SMN2KDM4EMAPTALOX15 | |
| SCHEMBL28635370 | 0.74 | ALOX12 (0.50) | ALDH1A1GAAMAPTMEN1HPGD | |
| SCHEMBL28635369 | 0.74 | ALOX12 (0.50) | ALDH1A1GAAMAPTMEN1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2376074-B1 | METHOD FOR IMPROVED BIOACTIVATION OF MEDICATIONS | DRITTE PATENTPORTFOLIO BETEILI (DE) | 2019-03-13 | — | — | EP | disclosed |
| US-20120077876-A1 | Method For Improved Bioactivation Of Pharmaceuticals | DRITTE PATENTPORTFOLIO BETEILIGUNGSGESELLSCHAFT MBH & CO. KG (DE) | 2012-03-29 | — | — | US | disclosed |
| CN-102378628-A | Method for improved bioactivation of medications | UNIV KIEL CHRISTIAN ALBRECHTS | 2012-03-14 | — | — | CN | disclosed |
| EP-2376074-A1 | METHOD FOR IMPROVED BIOACTIVATION OF MEDICATIONS | Dritte Patentportfolio Beteiligungsgesellschaft mbH & Co. KG (DE) | 2011-10-19 | — | — | EP | disclosed |
| WO-2010078867-A1 | METHOD FOR IMPROVED BIOACTIVATION OF MEDICATIONS | CHRISTIAN-ALBRECHTS-UNIVERSITÄT ZU KIEL (DE) | 2010-07-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120077876-A1 | Method For Improved Bioactivation Of Pharmaceuticals | CYP2B6, CYP1A2, CYP2D6 | TSHR 298/4885ALDH1A1 95/4885NPSR1 249/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.