Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3096869 | 0.83 | KDM4E (0.30) | KDM4ETSHRTDP1 | |
| SCHEMBL12451147 | 0.79 | KDM4E (0.37) | KDM4ETSHRTDP1 | |
| SCHEMBL11290143 | 0.77 | KDM4E (0.40) | KDM4ETSHRTDP1 | |
| Lithium Ion SCHEMBL18008644 | 0.75 | KDM4E (0.34) | KDM4ETSHRTDP1 | |
| Potassium Ion SCHEMBL11902986 | 0.75 | KDM4E (0.34) | KDM4ETSHRTDP1 | |
| SCHEMBL11902989 | 0.75 | KDM4E (0.39) | KDM4ETSHRTDP1 | |
| SCHEMBL18008876 | 0.75 | KDM4E (0.34) | KDM4ETSHRTDP1 | |
| SCHEMBL1766721 | 0.71 | CA2 (0.42) | — | |
| SCHEMBL202580 | 0.70 | KDM4E (0.38) | KDM4ETSHRTDP1 | |
| Dimethylamine SCHEMBL18008328 | 0.70 | KDM4E (0.35) | KDM4ETSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5821357-A | REACTING ALPHA-ANOMER ENRICHED 2,2-DIFLUOROCARBOHYDRATE WITH AT LEAST TWO MOLAR EQUIVALENTS OF METAL DERIVATIVE OF NUCLEOBASE IN LOW FREEZING INERT SOLVENT | ELI LILLY AND COMPANY (US) | 1998-10-13 | — | — | US | claimed |
| EP-0577303-B1 | Stereoselective glycosylation process | LILLY CO ELI (US) | 1997-10-01 | — | — | EP | claimed |
| US-5648473-A | GLYCOSYLATION IN SOLVENT | ELI LILLY AND COMPANY (US) | 1997-07-15 | — | — | US | claimed |
| US-5594124-A | REACTING ALPHA-ANOMER ENRICHED 2,2-DIFLUOROCARBOHYDRATE WITH AT LEAST THREE MOLAR EQUIVALENTS OF PROTECTED NUCLEOBASE IN LOW FREEZING INERT SOLVENT | ELI LILLY AND COMPANY (US) | 1997-01-14 | — | — | US | claimed |
| EP-0577303-A1 | Stereoselective glycosylation process | ELI LILLY AND COMPANY (US) | 1994-01-05 | — | — | EP | claimed |
| US-5821357-A | REACTING ALPHA-ANOMER ENRICHED 2,2-DIFLUOROCARBOHYDRATE WITH AT LEAST TWO MOLAR EQUIVALENTS OF METAL DERIVATIVE OF NUCLEOBASE IN LOW FREEZING INERT SOLVENT | ELI LILLY AND COMPANY (US) | 1998-10-13 | — | — | US | disclosed |
| EP-0577303-B1 | Stereoselective glycosylation process | LILLY CO ELI (US) | 1997-10-01 | — | — | EP | disclosed |
| US-5648473-A | GLYCOSYLATION IN SOLVENT | ELI LILLY AND COMPANY (US) | 1997-07-15 | — | — | US | disclosed |
| US-5606048-A | REACTING A CONCENTRATED ALPHA- OR BETA-ANOMER ENRICHED 1-DEOXY-2,2-DIFLUOROCARBOHYDRATE OR 2-DEOXY-2-FLUOROCARBOHYDRATE WITH A MOLAR EQUIVALENT OF A NUCLEOBASE DERIVATIVE IN A HIGH BOILING INERT SOLVENT | ELI LILLY AND COMPANY (US) | 1997-02-25 | — | — | US | disclosed |
| US-5594124-A | REACTING ALPHA-ANOMER ENRICHED 2,2-DIFLUOROCARBOHYDRATE WITH AT LEAST THREE MOLAR EQUIVALENTS OF PROTECTED NUCLEOBASE IN LOW FREEZING INERT SOLVENT | ELI LILLY AND COMPANY (US) | 1997-01-14 | — | — | US | disclosed |
| US-5401838-A | Reaction of sulfonate furanose with nucleobase | ELI LILLY AND COMPANY (US) | 1995-03-28 | — | — | US | disclosed |
| US-5371210-A | Reacting alpha anomer enriched 2-deoxy-2,2-difluorocarbo-hydrate with nucleobase | ELI LILLY AND COMPANY (US) | 1994-12-06 | — | — | US | disclosed |
| EP-0577303-A1 | Stereoselective glycosylation process | ELI LILLY AND COMPANY (US) | 1994-01-05 | — | — | EP | disclosed |