Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Acrylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 3/20 | 0.40 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LDHA | P00338 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acrylic Acid SCHEMBL28051258 | 0.96 | LMNA (0.41) | LMNAALDH1A1TSHRFGFR4CA4 | |
| Acrylic Acid SCHEMBL1082680 | 0.96 | LMNA (0.47) | LMNAALDH1A1TSHRFGFR4CA4 | |
| Acrylic Acid SCHEMBL16257 | 0.96 | — | — | |
| Acrylic Acid SCHEMBL9408012 | 0.92 | LMNA (0.44) | LMNAALDH1A1TSHRFGFR4CA4 | |
| Acrylic Acid SCHEMBL9418472 | 0.92 | — | — | |
| Acrylic Acid SCHEMBL1367649 | 0.92 | — | — | |
| Acrylic Acid SCHEMBL10632946 | 0.92 | CA4 (0.50) | LMNAALDH1A1TSHRFGFR4CA4 | |
| Acrylic Acid SCHEMBL11033079 | 0.92 | — | — | |
| Acrylic Acid SCHEMBL21246905 | 0.92 | LMNA (0.44) | LMNAALDH1A1TSHRFGFR4CA4 | |
| Acrylic Acid SCHEMBL21246904 | 0.92 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5846657-A | Liquid crystal displays containing spacers and methods for producing the spacer | ROHM AND HAAS COMPANY (US) | 1998-12-08 | — | — | US | disclosed |
| US-5346954-A | Thermoplastic and thermoset polymer compositions | ROHM AND HAAS COMPANY (US) | 1994-09-13 | — | — | US | disclosed |
| US-5237004-A | Lilght-scattering and-or reduced gloss or matte surface finish | ROHM AND HAAS COMPANY (US) | 1993-08-17 | — | — | US | disclosed |