Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Acrylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 3/20 | 0.38 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LDHA | P00338 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acrylic Acid SCHEMBL8715994 | 0.96 | LMNA (0.44) | LMNAALDH1A1TSHRFGFR4CA4 | |
| Acrylic Acid SCHEMBL27617845 | 0.93 | LMNA (0.47) | LMNAALDH1A1TSHRFGFR4CA4 | |
| Acrylic Acid SCHEMBL311614 | 0.93 | LMNA (0.47) | LMNAALDH1A1TSHRFGFR4CA4 | |
| Acrylic Acid SCHEMBL16257 | 0.93 | — | — | |
| Acrylic Acid SCHEMBL1082680 | 0.93 | LMNA (0.47) | LMNAALDH1A1TSHRFGFR4CA4 | |
| Acrylic Acid SCHEMBL9418472 | 0.89 | — | — | |
| Acrylic Acid SCHEMBL5173948 | 0.89 | LMNA (0.44) | LMNAALDH1A1TSHRFGFR4CA4 | |
| Acrylic Acid SCHEMBL10632946 | 0.89 | CA4 (0.50) | LMNAALDH1A1TSHRFGFR4CA4 | |
| Acrylic Acid SCHEMBL21246904 | 0.89 | — | — | |
| Acrylic Acid SCHEMBL21246905 | 0.89 | LMNA (0.44) | LMNAALDH1A1TSHRFGFR4CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105330897-A | Sodium acrylate calcium carbonate activating agent | TAO RONGYAN | 2016-02-17 | — | — | CN | claimed |
| CN-105330897-A | Sodium acrylate calcium carbonate activating agent | TAO RONGYAN | 2016-02-17 | — | — | CN | disclosed |
| CN-105330897-A | Sodium acrylate calcium carbonate activating agent | TAO RONGYAN | 2016-02-17 | — | — | CN | disclosed |
| CN-105330897-A | Sodium acrylate calcium carbonate activating agent | TAO RONGYAN | 2016-02-17 | — | — | CN | disclosed |