SCHEMBL8716037

SCHEMBL8716037

O=Cc1cccc(OCCCCCCOc2cccc(C=O)c2)c1

nearest known ligand 0.62

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MAOA P21397 7/20 0.62
MAOB P27338 7/20 0.62
NPC1 O15118 2/20 0.55
RAB9A P51151 2/20 0.55
TDP1 Q9NUW8 1/20 0.55
SRC P12931 1/20 0.51
TLR4 O00206 1/20 0.49
TLR2 O60603 1/20 0.49
FURIN P09958 1/20 0.47
PRSS1 P07477 4/20 0.46
TSHR P16473 1/20 0.46
KCNA3 P22001 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8374654 1.00 MAOA (0.62) MAOAMAOBNPC1RAB9ATDP1
SCHEMBL8374655 1.00 MAOA (0.62) MAOAMAOBNPC1RAB9ATDP1
SCHEMBL30724528 0.98 MAOA (0.64) MAOAMAOBNPC1RAB9ATDP1
SCHEMBL5543437 0.92 MAOA (0.66) MAOAMAOBNPC1RAB9ATDP1
SCHEMBL7756955 0.92 TSHR (0.59) MAOAMAOBNPC1RAB9ATDP1
SCHEMBL10497968 0.92 TSHR (0.59) MAOAMAOBNPC1RAB9ATDP1
SCHEMBL6289516 0.92 TSHR (0.59) MAOAMAOBNPC1RAB9ATDP1
SCHEMBL8863665 0.92 TSHR (0.59) MAOAMAOBNPC1RAB9ATDP1
SCHEMBL3904389 0.92 TSHR (0.59) MAOAMAOBNPC1RAB9ATDP1
SCHEMBL584475 0.92 TSHR (0.59) MAOAMAOBNPC1RAB9ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3487931-B1 HIGH-STRENGTH RUBBER COMPOSITION MICHELIN & CIE (FR) 2022-04-20 EP disclosed
US-10647848-B2 Rubber composition with a high level of fluidity based on an aromatic aldehyde and an aromatic polyphenol COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2020-05-12 US disclosed
EP-3390536-B1 RUBBER COMPOSITION WITH A HIGH LEVEL OF FLUIDITY BASED ON AN AROMATIC ALDEHYDE AND AN AROMATIC POLYPHENOL MICHELIN & CIE (FR) 2019-10-16 EP disclosed
WO-2018015668-A1 HIGH-STRENGTH RUBBER COMPOSITION COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2018-01-25 WO disclosed
WO-2017103404-A1 RUBBER COMPOSITION WITH A HIGH LEVEL OF FLUIDITY BASED ON AN AROMATIC ALDEHYDE AND AN AROMATIC POLYPHENOL COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2017-06-22 WO disclosed
US-5807974-A POLYARYLENEVINYLENE RESIN KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 1998-09-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10647848-B2 Rubber composition with a high level of fluidity based on an aromatic aldehyde and an aromatic polyphenol AHR, POP1, RER1 MAOA 1663/4885MAOB 1866/4885NPC1 2496/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.