⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2468579 | 0.84 | LMNA (0.32) | — | |
| SCHEMBL1242411 | 0.81 | KDM4E (0.37) | — | |
| SCHEMBL2086403 | 0.81 | CA12 (0.43) | — | |
| SCHEMBL3840012 | 0.80 | — | — | |
| SCHEMBL1922708 | 0.78 | ALDH1A1 (0.46) | — | |
| SCHEMBL42300 | 0.78 | — | — | |
| SCHEMBL5406160 | 0.78 | — | — | |
| SCHEMBL2243930 | 0.78 | CA12 (0.47) | — | |
| SCHEMBL27809294 | 0.76 | — | — | |
| SCHEMBL9720322 | 0.75 | LMNA (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3837245-A1 | SUBSTITUED 4-AMINO-1H-IMIDAZO[4,5-C]QUINOLINE COMPOUNDS AND IMPROVED METHODS FOR THEIR PREPARATION | Innate Tumor Immunity, Inc. (US) | 2021-06-23 | — | — | EP | disclosed |
| WO-2020037094-A1 | SUBSTITUED 4-AMINO-1H-IMIDAZO[4,5-C]QUINOLINE COMPOUNDS AND IMPROVED METHODS FOR THEIR PREPARATION | INNATE TUMOR IMMUNITY, INC. (US) | 2020-02-20 | — | — | WO | disclosed |