SCHEMBL8716210

SCHEMBL8716210

CC(=O)CCCCCc1ccc(-c2ccccc2)cc1

nearest known ligand 0.67

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
HDAC2 Q92769 3/20 0.67
HDAC1 Q13547 2/20 0.67
MGLL Q99685 3/20 0.58
MAPT P10636 2/20 0.58
FFAR1 O14842 2/20 0.58
RXFP1 Q9HBX9 1/20 0.58
ALDH1A1 P00352 2/20 0.56
RARB P10826 4/20 0.53
MEN1 O00255 1/20 0.53
RARA P10276 1/20 0.53
MTOR P42345 1/20 0.53
KMT2A Q03164 1/20 0.53
ALOX5 P09917 1/20 0.51
MMP12 P39900 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11802541 0.98 HDAC2 (0.66) HDAC2HDAC1MGLLMAPTFFAR1
SCHEMBL8716886 0.93 FFAR1 (0.61) HDAC2HDAC1MGLLFFAR1ALDH1A1
SCHEMBL6213668 0.89 MAPT (0.71) HDAC2HDAC1MAPTRXFP1ALDH1A1
SCHEMBL5681573 0.89 MAPT (0.71) HDAC2HDAC1MAPTRXFP1ALDH1A1
SCHEMBL13498521 0.89 MAPT (0.71) HDAC2HDAC1MAPTRXFP1ALDH1A1
SCHEMBL24340640 0.89 MAPT (0.71) HDAC2HDAC1MAPTRXFP1ALDH1A1
SCHEMBL547835 0.89 MAPT (0.71) HDAC2HDAC1MAPTRXFP1ALDH1A1
SCHEMBL8104136 0.89 MAPT (0.71) HDAC2HDAC1MAPTRXFP1ALDH1A1
SCHEMBL2632727 0.89 MAPT (0.71) HDAC2HDAC1MAPTRXFP1ALDH1A1
SCHEMBL19149704 0.89 MAPT (0.71) HDAC2HDAC1MAPTRXFP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5741438-A Optically active biphenyl derivative, process for preparation thereof, liquid crystal composition containing the same as an effective component, and liquid crystal element using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-04-21 US disclosed
EP-0395390-B1 Optically active biphenyl derivative, process for preparation thereof, liquid crystal composition containing the same as effective component, and liquid crystal element using the same SUMITOMO CHEMICAL CO (JP) 1994-09-28 EP disclosed
EP-0395390-A1 Optically active biphenyl derivative, process for preparation thereof, liquid crystal composition containing the same as effective component, and liquid crystal element using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1990-10-31 EP disclosed