Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.54 |
| ▸ | GAA | P10253 | 4/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | CASP1 | P29466 | 2/20 | 0.54 |
| ▸ | CASP7 | P55210 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3357496 | 0.88 | MAPT (0.50) | MAPTALDH1A1KDM4EGAAHPGD | |
| SCHEMBL2809005 | 0.80 | KDM4E (0.57) | MAPTALDH1A1KDM4EGAAHPGD | |
| SCHEMBL8718220 | 0.80 | MAPT (0.43) | MAPTALDH1A1KDM4EGAAHPGD | |
| SCHEMBL27447975 | 0.78 | MAPT (0.44) | MAPTALDH1A1KDM4EGAAHPGD | |
| SCHEMBL29067027 | 0.77 | ALDH1A1 (0.54) | MAPTALDH1A1KDM4EGAAHPGD | |
| SCHEMBL8716259 | 0.77 | MAPT (0.55) | MAPTALDH1A1KDM4EGAAHPGD | |
| SCHEMBL5069247 | 0.76 | CYP3A4 (0.46) | MAPTALDH1A1KDM4EGAAHPGD | |
| SCHEMBL27783257 | 0.75 | KDM4E (0.46) | MAPTALDH1A1KDM4EGAAHPGD | |
| SCHEMBL30660134 | 0.75 | MAPT (0.48) | MAPTALDH1A1KDM4EGAAHPGD | |
| SCHEMBL3361354 | 0.75 | MAPT (0.47) | MAPTALDH1A1KDM4EGAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0870082-A1 | ENZYMATIC METHOD FOR DYEING | NOVO NORDISK BIOCHEM NORTH AMERICA (US) | 1998-10-14 | — | — | EP | disclosed |
| WO-1997023684-A1 | ENZYMATIC METHOD FOR DYEING | NOVO NORDISK BIOCHEM NORTH AMERICA, INC. (US) | 1997-07-03 | — | — | WO | disclosed |