Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 4/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 7/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | CASP1 | P29466 | 2/20 | 0.40 |
| ▸ | CASP7 | P55210 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3357496 | 0.87 | MAPT (0.50) | CYP3A4LMNACYP1A2MAOAGAA | |
| SCHEMBL248077 | 0.84 | LMNA (0.59) | CYP3A4LMNACYP1A2MAOAGAA | |
| SCHEMBL28751385 | 0.83 | GAA (0.58) | CYP3A4LMNACYP1A2MAOAGAA | |
| SCHEMBL6451827 | 0.81 | KDM4E (0.57) | CYP3A4LMNACYP1A2GAACYP2C9 | |
| SCHEMBL1417358 | 0.78 | PBRM1 (0.52) | CYP3A4LMNACYP1A2MAOAGAA | |
| SCHEMBL248078 | 0.76 | NPC1 (0.56) | CYP3A4LMNACYP1A2MAOAGAA | |
| SCHEMBL19228562 | 0.76 | GAA (0.48) | CYP3A4LMNAMAOAGAACYP2C9 | |
| SCHEMBL1259980 | 0.76 | MAPT (0.65) | CYP3A4LMNACYP1A2GAACYP2C9 | |
| SCHEMBL596784 | 0.76 | KMT2A (0.56) | CYP3A4LMNACYP1A2GAACYP2C9 | |
| SCHEMBL8716262 | 0.76 | MAPT (0.54) | CYP3A4LMNACYP1A2MAOAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1966119-A1 | PHOTOCROSSLINKABLE MATERIALS | Rolic AG (CH) | 2008-09-10 | — | — | EP | disclosed |
| WO-2007071091-A1 | PHOTOCROSSLINKABLE MATERIALS | ROLIC AG (CH) | 2007-06-28 | — | — | WO | disclosed |