Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8939789 | 0.95 | EPHX1 (0.47) | EPHX2G6PC1EPHX1KMT2AOPRM1 | |
| SCHEMBL1005726 | 0.89 | G6PC1 (0.47) | EPHX2G6PC1EPHX1HTTL3MBTL1 | |
| SCHEMBL20896988 | 0.83 | OPRM1 (0.44) | OPRM1 | |
| SCHEMBL18409970 | 0.81 | GRIN1 (0.43) | EPHX2G6PC1EPHX1OPRM1SLC18A3 | |
| SCHEMBL25239973 | 0.79 | HRH3 (0.44) | — | |
| SCHEMBL678829 | 0.77 | G6PC1 (0.50) | EPHX2G6PC1EPHX1 | |
| SCHEMBL6497263 | 0.77 | GRIN1 (0.53) | EPHX2G6PC1EPHX1HTTL3MBTL1 | |
| SCHEMBL6497259 | 0.77 | GRIN1 (0.53) | EPHX2G6PC1EPHX1HTTL3MBTL1 | |
| SCHEMBL7392306 | 0.76 | EPHX2 (0.43) | EPHX2EPHX1KMT2AOPRM1SLC18A3 | |
| SCHEMBL7665557 | 0.75 | G6PC1 (0.47) | EPHX2G6PC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0836610-A1 | DIGLYCOSYLATED 1,2-DIOLS AS MIMETICS OF SIALYL-LEWIS X AND SIALYL-LEWIS A | Novartis AG (CH) | 1998-04-22 | — | — | EP | claimed |
| WO-1997001569-A1 | DIGLYCOSYLATED 1,2-DIOLS AS MIMETICS OF SIALYL-LEWIS X AND SIALYL-LEWIS A | NOVARTIS AG (CH) | 1997-01-16 | — | — | WO | claimed |