Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK2 | O96017 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 9/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.41 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.41 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7335065 | 0.85 | LTA4H (0.54) | CHEK2LTA4HLMNAKDM4ESMN1; SMN2 | |
| SCHEMBL7324542 | 0.84 | HRH3 (0.53) | CHEK2LTA4HLMNAMAPK1 | |
| Hydrochloric Acid SCHEMBL7328923 | 0.84 | LTA4H (0.53) | CHEK2LTA4HLMNAKDM4ESMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7360839 | 0.84 | HRH3 (0.52) | CHEK2LTA4HLMNAMAPK1 | |
| SCHEMBL5728990 | 0.81 | CHEK2 (0.48) | CHEK2LTA4HSMN1; SMN2 | |
| SCHEMBL3866051 | 0.79 | CHEK2 (0.56) | CHEK2LTA4HTSHRMAPK1 | |
| Hydrochloric Acid SCHEMBL6561583 | 0.78 | CHEK2 (0.55) | CHEK2LTA4HTSHRMAPK1 | |
| SCHEMBL6053346 | 0.76 | CHEK2 (0.58) | CHEK2LTA4H | |
| SCHEMBL4965391 | 0.76 | LTA4H (0.64) | LTA4HPOLBSLC6A2 | |
| SCHEMBL6610218 | 0.75 | LTA4H (0.50) | CHEK2LTA4HCYP1A2CYP2D6CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5821252-A | PROLONGED SPASMOLYTIC AND ANESTHETIC ACITIVITY | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-10-13 | — | — | US | disclosed |
| US-5821252-A | PROLONGED SPASMOLYTIC AND ANESTHETIC ACITIVITY | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-10-13 | — | — | US | disclosed |