Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.57 |
| ▸ | RAB9A | P51151 | 5/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23812489 | 0.83 | ALDH1A1 (0.55) | ALDH1A1RAB9AMAPK1NPC1SMN1; SMN2 | |
| SCHEMBL6139502 | 0.82 | ALDH1A1 (0.62) | ALDH1A1RAB9AMAPK1NPC1SMN1; SMN2 | |
| SCHEMBL8504749 | 0.82 | ALDH1A1 (0.55) | ALDH1A1RAB9AMAPK1NPC1SMN1; SMN2 | |
| SCHEMBL12114030 | 0.79 | ALDH1A1 (0.77) | ALDH1A1RAB9AMAPK1NPC1SMN1; SMN2 | |
| SCHEMBL2588443 | 0.77 | ALDH1A1 (0.72) | ALDH1A1RAB9AMAPK1NPC1SMN1; SMN2 | |
| SCHEMBL23812435 | 0.77 | ALDH1A1 (0.58) | ALDH1A1RAB9AMAPK1NPC1SMN1; SMN2 | |
| SCHEMBL21027551 | 0.77 | ALDH1A1 (0.73) | ALDH1A1RAB9AMAPK1NPC1SMN1; SMN2 | |
| SCHEMBL23812450 | 0.77 | TDP1 (0.64) | ALDH1A1RAB9AMAPK1NPC1SMN1; SMN2 | |
| SCHEMBL11441199 | 0.76 | ALDH1A1 (0.62) | ALDH1A1RAB9AMAPK1NPC1SMN1; SMN2 | |
| SCHEMBL23812467 | 0.75 | ALDH1A1 (0.60) | ALDH1A1RAB9AMAPK1NPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756502-A | APPETITE SUPPRESSANTS AND ANTISECRETORY AGENTS | WARNER-LAMBERT COMPANY (US) | 1998-05-26 | — | — | US | disclosed |