SCHEMBL8716874

SCHEMBL8716874

CCC(C)(C)CCNc1ccc(Nc2ccccc2Cl)c2c1C(=O)OC21c2ccccc2Oc2ccccc21

nearest known ligand 0.32

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.32
ALDH1A1 P00352 1/20 0.31
CYP2C9 P11712 1/20 0.31
HPGD P15428 1/20 0.31
ALOX15 P16050 1/20 0.31
ALOX12 P18054 1/20 0.31
BRCA1 P38398 1/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4084681 0.87 KDM4E (0.36) CYP3A4ALDH1A1CYP2C9HPGDALOX15
SCHEMBL11035507 0.86 BRCA1 (0.35) CYP3A4ALDH1A1CYP2C9HPGDALOX15
SCHEMBL6439279 0.79 ALDH1A1 (0.37) CYP3A4ALDH1A1CYP2C9HPGDALOX15
SCHEMBL4379777 0.79 CYP3A4 (0.35) CYP3A4ALDH1A1CYP2C9HPGDALOX15
SCHEMBL10910338 0.77 GRK6 (0.37) ALDH1A1CYP2C9HPGDALOX15ALOX12
SCHEMBL9855468 0.76 CYP3A4 (0.33) CYP3A4ALDH1A1CYP2C9HPGDALOX15
SCHEMBL10347645 0.76 FTO (0.44) CYP3A4ALDH1A1CYP2C9HPGDALOX15
SCHEMBL10868252 0.75 ALDH1A1 (0.36) CYP3A4ALDH1A1CYP2C9HPGDALOX15
SCHEMBL9855220 0.75 ALDH1A1 (0.33) CYP3A4ALDH1A1CYP2C9HPGDALOX15
SCHEMBL3641991 0.74 HPGD (0.39) CYP3A4ALDH1A1CYP2C9HPGDALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5804529-A HEAT SENSITIVE RECORDING LAYER; BETWEEN TWO POLYMERIC OXYGEN BARRIER LAYERS MITSUBISHI PAPER MILLS LTD. (JP) 1998-09-08 US disclosed