SCHEMBL8716909

SCHEMBL8716909

C=CCNCCN(CC=C)CCN(CC)CC=C

nearest known ligand 0.36

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.36
MEN1 O00255 1/20 0.33
POLB P06746 1/20 0.33
KMT2A Q03164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9699428 0.88 TDP1 (0.33) TDP1
SCHEMBL10643000 0.86 KMT2A (0.43) TDP1MEN1POLBKMT2A
SCHEMBL4306829 0.83 TDP1 (0.35) TDP1MEN1KMT2A
SCHEMBL18465506 0.83 TDP1 (0.36) TDP1
SCHEMBL27095806 0.81 MEN1 (0.44) TDP1MEN1POLBKMT2A
SCHEMBL10833378 0.79 TDP1 (0.37) TDP1
SCHEMBL8597886 0.78 TDP1 (0.31) TDP1
Phosphoric Acid SCHEMBL1025029 0.76 KMT2A (0.36) TDP1MEN1POLBKMT2A
SCHEMBL10583240 0.75 PAOX (0.33) TDP1
SCHEMBL7938632 0.74 TDP1 (0.41) TDP1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5744677-A USING CATALYST WHICH IS A MIXTURE OF A CHROMIUM COMPLEX AND AN ALUMINOXANE AMOCO CORPORATION (US) 1998-04-28 US disclosed
EP-0537609-B1 Ethylene oligomerization ALBEMARLE CORP (US) 1996-08-14 EP disclosed
EP-0537609-A2 Ethylene oligomerization ALBEMARLE CORPORATION (US) 1993-04-21 EP disclosed