Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | CCR2 | P41597 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CCR3 | P51677 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7670875 | 0.87 | OPRM1 (0.40) | OPRK1BIRC2CCR2KCNH2POLB | |
| SCHEMBL27470540 | 0.87 | OPRM1 (0.40) | OPRK1BIRC2CCR2KCNH2POLB | |
| SCHEMBL8717284 | 0.84 | GAA (0.38) | OPRK1ALDH1A1THRBATML3MBTL1 | |
| SCHEMBL5648709 | 0.83 | HPGD (0.42) | ALDH1A1BIRC2SMN1; SMN2RECQL | |
| SCHEMBL13247613 | 0.83 | HPGD (0.42) | ALDH1A1BIRC2SMN1; SMN2RECQL | |
| SCHEMBL6492710 | 0.82 | BIRC2 (0.42) | OPRK1BIRC2CCR2KCNH2CHRM1 | |
| SCHEMBL6492709 | 0.82 | BIRC2 (0.42) | OPRK1BIRC2CCR2KCNH2CHRM1 | |
| SCHEMBL28750702 | 0.82 | ALDH1A1 (0.43) | ALDH1A1THRBATML3MBTL1GAA | |
| SCHEMBL29270907 | 0.82 | ALDH1A1 (0.43) | ALDH1A1THRBATML3MBTL1GAA | |
| SCHEMBL6492712 | 0.82 | BIRC2 (0.42) | OPRK1BIRC2CCR2KCNH2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0569802-B1 | Arylacetamides | MERCK PATENT GMBH (DE) | 1998-07-15 | — | — | EP | disclosed |
| US-5532266-A | Acrylacetamides | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1996-07-02 | — | — | US | disclosed |
| EP-0569802-A1 | Arylacetamides | MERCK PATENT GmbH (DE) | 1993-11-18 | — | — | EP | disclosed |