Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR4 | Q13639 | 10/20 | 0.60 |
| ▸ | HTR3A | P46098 | 10/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8717351 | 1.00 | HTR4 (0.60) | HTR4HTR3ACYP3A4 | |
| SCHEMBL8713436 | 0.91 | HTR3A (0.51) | HTR4HTR3ACYP3A4 | |
| SCHEMBL8717229 | 0.91 | HTR3A (0.51) | HTR4HTR3ACYP3A4 | |
| SCHEMBL8713439 | 0.91 | HTR3A (0.51) | HTR4HTR3ACYP3A4 | |
| SCHEMBL8717225 | 0.91 | HTR3A (0.51) | HTR4HTR3ACYP3A4 | |
| SCHEMBL8714841 | 0.85 | HTR4 (0.82) | HTR4HTR3ACYP3A4 | |
| SCHEMBL8714839 | 0.85 | HTR4 (0.82) | HTR4HTR3ACYP3A4 | |
| SCHEMBL8714417 | 0.84 | HTR4 (0.60) | HTR4HTR3A | |
| SCHEMBL8714411 | 0.84 | HTR4 (0.60) | HTR4HTR3A | |
| SCHEMBL9079955 | 0.82 | HTR4 (0.54) | HTR4HTR3ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708105-B1 | 5-HT4 receptor agonists | NISSHIN FLOUR MILLING CO (JP) | 1998-12-23 | — | — | EP | disclosed |
| EP-0708105-A1 | 5-HT4 receptor agonists | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1996-04-24 | — | — | EP | disclosed |