Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | HPD | P32754 | 6/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.43 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.43 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.43 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | CFD | P00746 | 1/20 | 0.41 |
| ▸ | F11 | P03951 | 1/20 | 0.41 |
| ▸ | TPSB2 | P20231 | 1/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.41 |
| ▸ | PPIA | P62937 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8719056 | 0.84 | PTGER1 (0.56) | HPDALDH1A1LMNAPOLBHTT | |
| SCHEMBL10831662 | 0.83 | PTGER1 (0.46) | HPDALDH1A1LMNAPOLBHTT | |
| SCHEMBL8714342 | 0.81 | TSHR (0.55) | TSHRPTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL10506139 | 0.80 | HPD (0.47) | HPDALDH1A1LMNAPOLBHTT | |
| SCHEMBL6339163 | 0.79 | HPD (0.46) | HPDMEN1KMT2ACYP19A1FOLH1 | |
| SCHEMBL6348032 | 0.79 | HPD (0.47) | HPDALDH1A1MEN1KMT2ACYP19A1 | |
| SCHEMBL15013285 | 0.77 | MAPT (0.55) | HPDALDH1A1MEN1KMT2ACYP19A1 | |
| SCHEMBL6598985 | 0.76 | TSHR (0.49) | TSHRALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL2986814 | 0.75 | HPD (0.57) | HPDALDH1A1PTGER1MEN1KMT2A | |
| SCHEMBL647866 | 0.73 | TDP1 (0.56) | TSHRHPDALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708105-B1 | 5-HT4 receptor agonists | NISSHIN FLOUR MILLING CO (JP) | 1998-12-23 | — | — | EP | disclosed |
| US-5684003-A | GASTROINTESTINAL DISORDERS OR ANTIULCER AGENTS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1997-11-04 | — | — | US | disclosed |
| EP-0708105-A1 | 5-HT4 receptor agonists | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1996-04-24 | — | — | EP | disclosed |