Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | CFD | P00746 | 3/20 | 0.47 |
| ▸ | F11 | P03951 | 3/20 | 0.47 |
| ▸ | TPSB2 | P20231 | 3/20 | 0.47 |
| ▸ | PTGER1 | P34995 | 5/20 | 0.46 |
| ▸ | PTGER4 | P35408 | 4/20 | 0.46 |
| ▸ | PTGER3 | P43115 | 4/20 | 0.46 |
| ▸ | PTGER2 | P43116 | 4/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.44 |
| ▸ | PLG | P00747 | 1/20 | 0.44 |
| ▸ | PLAU | P00749 | 1/20 | 0.44 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.44 |
| ▸ | F7 | P08709 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11094009 | 0.83 | PTGER1 (0.61) | CFDF11TPSB2PTGER1PTGER4 | |
| SCHEMBL8717352 | 0.81 | TSHR (0.50) | TSHRCFDF11TPSB2PTGER1 | |
| SCHEMBL11092098 | 0.80 | CFD (0.51) | CFDF11TPSB2PTGER1PTGER4 | |
| SCHEMBL6599999 | 0.77 | TSHR (0.54) | TSHRL3MBTL1MAPTLTA4H | |
| Hydrochloric Acid SCHEMBL28288311 | 0.74 | MAPK1 (0.46) | CFDF11TPSB2PTGER1PTGER4 | |
| SCHEMBL22654317 | 0.73 | ABCB11 (0.54) | CFDF11TPSB2PTGER1PTGER4 | |
| SCHEMBL873430 | 0.73 | TSHR (1.00) | TSHRL3MBTL1MAPTMAPK1 | |
| SCHEMBL2988197 | 0.73 | L3MBTL1 (0.56) | CFDF11TPSB2PTGER1PTGER4 | |
| SCHEMBL31757763 | 0.73 | L3MBTL1 (0.56) | CFDF11TPSB2PTGER1PTGER4 | |
| SCHEMBL11828242 | 0.72 | MAPT (0.64) | TDP1L3MBTL1MAPTMAPK1LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708105-B1 | 5-HT4 receptor agonists | NISSHIN FLOUR MILLING CO (JP) | 1998-12-23 | — | — | EP | disclosed |
| US-5684003-A | GASTROINTESTINAL DISORDERS OR ANTIULCER AGENTS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1997-11-04 | — | — | US | disclosed |
| EP-0708105-A1 | 5-HT4 receptor agonists | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1996-04-24 | — | — | EP | disclosed |